Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

“…In vivo experiments showed that MMP9, PLA2G7, CD52, SPP1, FYB, and PLCB2 mRNA levels were up-regulated in adipose, aortic tissues and serum of OB and AS model mice, CLEC5A was up-regulated in aorta and serum, and PRKCB was up-regulated in adipose and serum.Conclusion: MMP9, PLA2G7, CD52, CLEC5A, SPP1, and FYB may serve as potential diagnostic biomarkers for CAS in obese populations. …”
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma by Yonglin Luo, Wenyang Wei, Yaxuan Huang, Jun Li, Weiling Qin, Quanxiang Hao, Jiemei Ye, Zhe Zhang, Yushan Liang, Xue Xiao, Yonglin Cai

“…Moreover, the expression of RBL2, E2F1, and CDC25C were significantly correlated with the expression of caspase family genes. Finally, the lower mRNA and protein expression of RBL2 were validated in NPC cell lines and tissues. …”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Result The mean age of this study population was 35.60 years with M: F ratio 1.27:1. Majority presented with symptoms of nasal obstruction with nasal discharge. …”
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Evaluación de las competencias clínicas prácticas en estudiantes de terapia manual ortopédica a través del Examen Clínico Objetivo Estructurado (ECOE): Experiencia piloto en la Uni... by Sebastian Eustaquio Martin Perez, Isidro Miguel Martín Pérez, Eva Rodríguez Lorenzo, Andrea Cabrera Fuentes, Yeray Rodríguez Rodríguez, Josué González Fernández, José Luis Alonso Pérez

“…Métodos: Se realizó un estudio descriptivo en una muestra de estudiantes de posgrado (n=21, M=10, V=11, 24,61 años) entre el 1 de febrero y el 31 de julio de 2023 en el Hospital Simulado de la Universidad Europea de Canarias (Tenerife, España). …”
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Notation publications in the context of musical life in Lithuania in the XVI-XVII centuries by Jūratė Trilupaitienė

“…The greater part of books published in Vilnius in 1598 (M. Petkevičius' Katekizmas) and in Kėdainiai (Knygos nobažnystės krikščioniškos in 1653) were hymnals whose hymns were based on melodies from the above-mentioned Vilnius publications. …”
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Effect of differences in vascular anatomy on surgical outcomes of left pancreatectomy: a retrospective study by Masahiro Fukada, Noriki Mitsui, Takeshi Horaguchi, Yuji Hatanaka, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Shigeru Kiyama, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi

“…In open-LP cases, high body mass index (> 24 kg/m2; OR 7.24; 95% CI 1.89–36.34; p < 0.01), tumor location (pancreatic body; OR 6.89; 95% CI 1.79–33.79; p < 0.01), and the SpA type (type 2; OR 5.86; 95% CI 1.72–24.65; p < 0.01) showed significant association with prolonged operations. …”
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The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…In a randomised crossover design, nine young healthy men (aged 27.8 ± 4.9 years; BMI 24.4 ± 2.4 kg/m2) completed 30 min of high-intensity aerobic exercise (90–95% heart rate reserve) after glucocorticoid or placebo ingestion. …”
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Association of Serum Ferritin Levels With Obstructive Sleep Apnea in Overweight/Obese US Populations: A Population-Based Study From the NHANES by Zhang Y, Zhou P, Xu C, Su H, Li R, Sun L, Yang Y

“…A non-linear U-shaped association was observed between ferritin levels and OSA risk (P-non-linear = 0.029), with an inflection point at ln-transformed ferritin of 4.58 (corresponding to a serum ferritin concentration of 97.51 ng/mL). In female OSA patients, elevated ferritin levels were associated with increased all-cause mortality risk (Q4 vs Q2: HR: 5.46, 95% CI: 1.18– 25.16, P = 0.029, P for trend = 0.032).Conclusion: Ferritin levels in overweight/obese individuals show a U-shaped relationship with OSA risk, and elevated levels correlate with increased all-cause mortality in female overweight/obese OSA patients. …”
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Evaluation method and application for in-situ stress in No. 8+9 coal seam, southern Shenfu block, northeastern margin of Ordos Basin by Jiawei WU, Wei TANG, Yanhe ZHU, Cunwu WANG, Yongjing TIAN, Jingyu ZI, Jianghao YANG, Xian SHI

“…In 20 wells, calculations of the in-situ stress showed that the vertical principal stress in the No. 8+9 coal seam with a vertical depth of 1 902-2 181 m was 47-54 MPa. The minimum horizontal principal stress was 35-44 MPa, and the maximum was 42-50 MPa. …”
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Association between exposure to ambient air pollutants and metabolic syndrome in the vicinity of the Taklamakan Desert by Zhe Wang, Weidong Ji, Yushan Wang, Lin Li, Kai Wang, Hongze Liu, Yining Yang, Yi Zhou

“…Non-linear analysis indicated a significant association between all pollutants and MetS prevalence. A 10 μg/m³ increase in concentration was associated with the following respective odds ratios: PM1 (1.341, 95 % CI: 1.331, 1.351), PM2.5 (1.036, 95 % CI: 1.034, 1.037), PM10 (1.006, 95 % CI: 1.005, 1.007), O3 (1.385, 95 % CI: 1.374, 1.396), and CO (1.015,95 %, CI: 1.0147, 1.016). …”
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Dual targeting of breast cancer by chitosan/poly lactic-co-glycolic acid nanodelivery systems: Surface activation with folic acid/aptamers, and co-encapsulated with Sorafenib and q... by Asghar Narmani, Saeid Ganji, Maryam Amirishoar, Fatemeh Hajikarimi, Aynaz Mazandarani, Mahya Karimi, Ali Mohammadinejad, Azin Azadpour, Roghayyeh Jahedi, Elham Assadpour, Seid Mahdi Jafari

“…Nanometric size (50 to 110 nm), semi-spherical and spherical shape, rough surface, and near-to-neutral surface charge (3.8 mV) were measured for Apt-PLGA-So-Qu-CS-FA nanocarriers. …”
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Peripheral versus central cannulation of VA-ECMO for primary graft dysfunction after heart transplantation: A systematic review and meta-analysis by Eduard Ródenas-Alesina, MD, Aleix Olivella, MD, Ani Orchanian-Cheff, MiST, Farid Foroutan, PhD, Yasbanoo Moayedi, MD, MSc, Vivek Rao, MD, PhD, Filio Billia, MD, PhD, Heather J. Ross, MD, MHSc, Ana Carolina Alba, MD, PhD, Natasha Aleksova, MD, MSc

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Dye sensitized photocatalytic degradation of congo red and rhodamine B by 1,3,5-Benzenetricarboxylic acid based metal organic frameworks Ni3(BTC)2.12H2O, (Ni0.8Co0.2)3(BTC)2.12H2O... by Kavitha Karuppiah, Anushree Raju, Anuradha Natarajan, Swedha Mohan, Dhinakaran Subramani, Kumaran Rajendran, Vanjinathan Mahalingam, Gopalakrishnan Arumugam, Samikannu Prabu, Kung-Yuh Chiang, Vasanthi Rajaraman

“…The exceptional performance of Cu₃(BTC)₂ is attributed to its large surface area (1064 m2g−1). The incorporation of cobalt into the (Ni₀.₈Co₀.₂)₃(BTC)₂ framework enhanced the degradation rates compared to pure Ni₃(BTC)₂. …”
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Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“….-32-13T>G mutation with the U1+1 snRNA increased the amount of normal GAA mRNA by 1,8 fold and the GAA enzymatic activity by 70%. …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Its derivatives, such as 13p, exhibit enhanced potency by arresting the G2/M phase and targeting drug-resistant cells with minimal toxicity. …”
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Associations of PM2.5 with Chronic Obstructive Pulmonary Disease in Shipyard Workers: A Cohort Study by Nguyen Thanh Tung, Ching-Huang Lai, Chih-Hong Pan, Wei-Liang Chen, Chung-Ching Wang, Che-Wei Liang, Chi-Yu Chien, Kai-Jen Chuang, Huynh Nguyen Xuan Thao, Hoang Ba Dung, Tran Phan Chung Thuy, Hsiao-Chi Chuang

“…We observed that a 1-µg m−3 increase in PM2.5 deposition in lung regions (total lung, and head and nasal, tracheobronchial, and alveolar regions) was associated with decreases (β coefficients) in FeNO, FVC, FEV1, PEF, FEF25%–75%, FEF25%, and FEF50% (all p < 0.05). …”
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Effects of exercise and exercise timing on energy intake and appetite control in Danish individuals with overweight or obesity with and without type 2 diabetes: a protocol for a ra... by Louise Groth Grunnet, Martin Bæk Blond, Jonas Salling Quist, Kristine Beaulieu, Graham Finlayson, Kristine Færch, Lea Jalking, Natja Poder Launbo, Marie Møller Jensen, Hanne Enghoff Pedersen, Marina Kjærgaard Gerstenberg

“…Fifty-eight women and men (aged 18–75 years) with overweight or obesity (body mass index ≥25 kg/m2) with or without T2D will be recruited. All participants will complete a screening and baseline visit followed by four test visits: two morning visits and two late afternoon visits. …”
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Features of development and progression of colorectal cancer on a background of ulcerative colitis by I. L. Khalif, V. N. Kashnikov, A. V. Gusev, O. V. Golovenko, K. V. Bolikhov, L. L. Kapuller, A. N. Kuznetsov, A. V. Vasilchenko

“…In 12 patients (18,5%) CRC was characterized by primary multifocal with up to 5 tumors in different regions of the large intestine in T4N0M0stage. In 7 (10,8%) cases of 65 the signs of dysplasia of intestinal epithelium were not revealed, in 24 (36,9%) dysplasia of moderate degree and in 34 (52,3%) – high degree was observed. …”
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Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency by Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E. Goldfinger, Jeremy G.T. Wurtzel, Kiwon Lee, Michele P. Lambert, Mortimer Poncz, A. Koneti Rao

“…Results: Platelet F13A1 mRNA and protein were decreased in our index patient and in 2 siblings from an unrelated family with RHD. …”
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Liposome-like encapsulation of fish oil-based self-nano emulsifying formulation for improved bioavailability by Iqbal Ahmad, Aparana Dogra, Tanya Nagpal, Chandvi Sharma, Sudhakar Singh, Nikhil Shaiva, Gaurav Saini, Kanishk Luhach

“…The optimized formulation exhibited significantly smaller particle sizes (100–300 nm), low PDI (0.149–0.303), and a stable zeta potential(-32.5 to -27.9 mV), potentially contributing to improved absorption and stability. …”
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