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9121
Meta-analysis to evaluate the comparative effectiveness of enzalutamide and abiraterone acetate for first-line treatment of metastatic castration-resistant prostate cancer in real-...
Published 2025-02-01“…IntroductionAndrogen-receptor pathway inhibitors such as abiraterone and enzalutamide have demonstrated clinical benefit in patients with metastatic castration-resistant prostate cancer (mCRPC). The aim of this study was to conduct a meta-analysis of published real-world evidence studies comparing outcomes among patients treated with enzalutamide or abiraterone in the first-line setting.MethodsWe conducted a systematic literature review to identify eligible studies. …”
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9122
Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway
Published 2025-02-01“…Methods In this study, T2DM model was established using high fat diet combined with streptozocin (STZ) injection in C57BL/6 mice, and then exposed to multiple 75 mGy LDR every other day for one month. The changes of blood glucose levels, body weight, and the damage of pancreas were measured. …”
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9123
Next-generation calcium oxide nanoparticles: A breakthrough in energy storage and humidity sensing
Published 2025-03-01“…Supercapacitance calculated from CV study was 23.45–72.22 F/g at different scan rates ranging from 2.5 to 100 mV/s, while supercapacitance values obtained from GCD study were 11.77 to 30.18 F.g−1 at various current density ranges from 0.5 to 5 A.g−1. …”
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9124
Weight Change and Predictors of Weight Change Among Patients Initiated on Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide or Bictegravir/Emtricitabine/Tenofovir Alafenamid...
Published 2021-06-01“…Patients initiated on BIC/FTC/TAF experienced greater weight and BMI increases between the pre-index period and each measurement of the post-index period than patients initiated on DRV/c/FTC/TAF, although results were only statistically significant at 9 months post-index (weight: mean difference=2.50 kg, *P*=0.005; BMI: mean difference=0.66 kg/m^2^, *P*=0.027). A common predictor of weight or BMI gain ≥5% among patients in both cohorts was female gender (DRV/c/FTC/TAF: odds ratio \[OR\]=5.92, *P*=0.014; BIC/FTC/TAF: OR=2.00, *P*\<0.001). …”
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9125
Inhibition of Ultraviolet B-induced Apoptosis in Fibroblasts by Human Umbilical Cord Blood Mesenchymal Stem Cell Conditioned Media via the Phosphatidylinositol-3-Kinase/Akt Pathway
Published 2025-01-01“…NIH3T3 cells were pretreated with/without 50 μM LY294002, treated with/without 10% CM-hUCB-MSC, and then irradiated with/without UVB. …”
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9126
RETRACTED ARTICLE: NR3C2 affects the proliferation and invasiveness of colon cancer cells through the Wnt/β-Catenin signaling pathway
Published 2024-09-01“…Abstract Purpose The aim of this study was to explore the potential correlation between the nuclear receptor subfamily 3 group C member 2 (NR3C2) and outcomes of colon cancer, along with the mechanisms underlying this association. Method mRNA (messenger RNA) data and clinical records pertaining to colon cancer were retrieved from The Cancer Genome Atlas (TCGA) database. …”
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9127
Effects of royal jelly consumption on clinical outcomes in patients with ischemic stroke: A triple-blind randomized controlled trial
Published 2025-02-01“…Additionally, serum nitric oxide levels increased in the RJ group (adjusted mean difference, 10.18 nmol/mL [95 % CI, 0.51 to 19.86]) post-intervention compared to the control group. …”
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9128
Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study
Published 2025-02-01“…RT-qPCR confirmed these trends, showing reduced mRNA levels of IL-1β and TNF-α and increased YAP expression in the LPS + DMOG group (P < 0.0001). …”
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9129
Структура та фазовий склад плівок Fe–Si–B-Cu–Nb та Fe–Si–B-Ni–Mo
Published 2024-06-01“…У роботі визначено умови отримання плівок з низькими значеннями температурного коефіцієнта електричного опору (-0.000009)·1/K та коерцитивної сили (HC ~ 11 A/m). …”
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9130
Role of serum sodium on heart, anemia, and diabetes patients
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9131
Comprehensive genomic and transcriptomic analyses of the anaerobic degradation of microcystin in Alcaligenes faecalis D04
Published 2025-01-01“…In this study, a bacterium capable of degrading MC-LR with a degradation efficiency of 0.303 µg/mL/d under anaerobic conditions was isolated from water. …”
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9132
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9133
El forraje verde hidropónico como una alternativa productiva en Patagonia Sur: Productividad y calidad nutricional de dos variedades de cebada (Hordeum vulgare)
Published 2018-01-01“…No se encontraron diferencias significativas en productividad entre las variedades, obteniéndose entre 18 y 21 kg/m2 de FVH en fresco. Asimismo, tampoco se encontraron diferencias significativas en cantidad de biomasa producida según el nivel de luz recibido, obteniendo similares rendimientos las bandejas ubicadas en una mejor posición lumínica que las ubicadas en el piso inferior. …”
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9134
Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice
Published 2025-01-01“…In contrast, the highest dose (50.0 mg/kg) resulted in elevated liver enzyme levels, indicative of liver damage, while lipid levels decreased. Notably, the mRNA or protein levels of SCD1 were upregulated in response to the lower doses of HQ (12.5 and 25.0 mg/kg), whereas AMPK activation and enhanced autophagy were observed in the 50.0 mg/kg HQ-treated group, reflecting an energy stress response. …”
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9135
Chemical Composition Characteristics and Source Apportionment of PM2.5 in Ceramic Industrial Base during Winter
Published 2022-03-01“…The results showed that the average PM2.5 concentration during sampling period was 134 ± 74.7 µg m−3, which exceeding World Health Organization (WHO) Air Quality Guidelines levels. …”
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9136
Comprehensive Analysis of VOCs in an Industrial Harbor City: Spatiotemporal Distribution, Health Risk, and Potential Sources
Published 2024-06-01“…OFP results indicated that toluene was primary OFP contributor, accounting for an average of 30.4%, followed by C2-VOCs at 16.2% and m/p-xylenes at 12.5%, collectively contributing nearly 60% to OFP. …”
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9137
PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic
Published 2025-01-01“…Remarkably, arsenic exposure increased the expression levels of Perilipin 5 (PLIN5), a lipid droplet-associated protein, both at the mRNA and protein levels. Moreover, silencing PLIN5 influenced arsenic-induced lipolysis. …”
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9138
Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B
Published 2025-02-01“…The combination of shear wave elastography (SWE), mPage-B score, age and type 2 diabetes mellitus had an area under the curve of 0.838 (P < 0.001) in predicting the occurrence of HCC. …”
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9139
Diurnal and Daily Variations of PM2.5 and its Multiple-Wavelet Coherence with Meteorological Variables in Indonesia
Published 2024-01-01“…Meanwhile, the investigation on the extreme rise of PM2.5 in Pontianak due to peatland forest fires using HYSPLIT shows that emission from the surrounding area significantly raises the maximum half-hourly in Pontianak to 700 μg m−3.…”
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9140
Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings
Published 2025-02-01“…Reverse transcription-polymerase chain reaction was performed for the NTRK gene fusion and EGFR-ITDs in all cases. Comprehensive mRNA analysis was performed using the nCounter® Gene Expression Assay. …”
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