Mechanism of adenosine monophosphate-activated protein kinase promoting lower extremity varicose veins development via cytoskeletal dynamics

Mechanism of adenosine monophosphate-activated protein kinase promoting lower extremity varicose veins development via cytoskeletal dynamics

Abstract Objective This study aimed to investigate the potential involvement of 5'-AMP-activated protein kinase (AMPK) in the pathogenesis of lower-extremity varicose veins (VV). Methods In this study, 8 patients with CEAP stage C6 chronic venous disease and 8 age-matched healthy controls were...

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Bibliographic Details
Main Authors: Yongmei Zhang, Zhinan Ju, Kanghui Dai, Liqun Wan, Guangmao Zhou, Yanchun Ji, Jiehua Qiu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Lower extremity varicose vein
AMPK
Cofilin
HSP20
VSMC
Online Access:https://doi.org/10.1186/s12872-025-04821-6
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https://doi.org/10.1186/s12872-025-04821-6

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