Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fidelity of this complex process. Transcripts that fai...

Full description

Saved in:
Bibliographic Details
Main Authors: Gonzalo I. Mendoza-Ochoa, J. David Barrass, Isabella E. Maudlin, Jean D. Beggs
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Auxin
pre-mRNA splicing
Prp22
protein depletion
yeast
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2019.1657788
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items