Rapid detection of antibiotic resistance in Burkholderia pseudomallei using MALDI-TOF mass spectrometry

Rapid detection of antibiotic resistance in Burkholderia pseudomallei using MALDI-TOF mass spectrometry

Abstract Antibiotic resistance in Burkholderia pseudomallei (Bp) is a growing public health concern requiring urgent attention. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid bacterial identification tool with potential for future d...

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Main Authors: Nut Nithimongkolchai, Yothin Hinwan, Kanwara Trisakul, Lumyai Wonglakorn, Ploenchan Chetchotisakd, Auttawit Sirichoat, Arnone Nithichanon, Sorujsiri Chareonsudjai, Pisit Chareonsudjai, Jody Phelan, Taane G. Clark, Kiatichai Faksri
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
MALDI-TOF MS
Machine learning
Burkholderia pseudomallei
Minimum inhibitory concentration
Antibiotic resistance
Geographical distribution
Online Access:https://doi.org/10.1038/s41598-025-07687-y
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https://doi.org/10.1038/s41598-025-07687-y

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