Visualization of the existence of LEAP2 in the nucleus accumbens and its role in amphetamine-induced locomotor activity

Visualization of the existence of LEAP2 in the nucleus accumbens and its role in amphetamine-induced locomotor activity

Abstract The nucleus accumbens (NAcc) is a key brain region in reward circuitry, mediating responses to psychostimulants, such as amphetamine (AMPH), including locomotor activity. This effect is known to be enhanced by the orexigenic neuropeptide ghrelin acting through growth hormone-secretagogue re...

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Bibliographic Details
Main Authors: Seohyeon Lee, Ga Young Yoo, Hyung Shin Yoon, Jeong-Hoon Kim
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Brain
Subjects:
LEAP2
Nucleus accumbens
Amphetamine
Neuropeptide
Locomotor activity
Online Access:https://doi.org/10.1186/s13041-025-01227-5
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