DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function

DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function

Abstract The coordinated development of cortical circuits composed of excitatory and inhibitory neurons is critical for proper brain function, and disruptions are linked to a spectrum of neuropsychiatric disorders. While excitatory neurons are generated locally in the cortical proliferative zones, i...

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Main Authors: Julia Reichard, Philip Wolff, Song Xie, Ke Zuo, Camila L. Fullio, Jian Du, Severin Graff, Jenice Linde, Can Bora Yildiz, Georg Pitschelatow, Gerion Nabbefeld, Lilli Dorp, Johanna Vollmer, Linda Biemans, Shirley Kempf, Minali Singh, K. Naga Mohan, Chao-Chung Kuo, Tanja Vogel, Paolo Carloni, Simon Musall, Geraldine Zimmer-Bensch
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62114-0
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https://doi.org/10.1038/s41467-025-62114-0

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