Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.

Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.

Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease outcome have been identified. We hypothesized that macrophages from individuals with different clinical manifestations of Mycobacterium tuberculosis (Mtb) infection would have distinct gene expressio...

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Main Authors: Nguyen Thuy Thuong Thuong, Sarah J Dunstan, Tran Thi Hong Chau, Vesteinn Thorsson, Cameron P Simmons, Nguyen Than Ha Quyen, Guy E Thwaites, Nguyen Thi Ngoc Lan, Martin Hibberd, Yik Y Teo, Mark Seielstad, Alan Aderem, Jeremy J Farrar, Thomas R Hawn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000229&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000229&type=printable

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