PepO and CppA modulate Streptococcus sanguinis susceptibility to complement immunity and virulence

PepO and CppA modulate Streptococcus sanguinis susceptibility to complement immunity and virulence

Streptococcus sanguinis is a ubiquitous commensal species of the oral cavity commonly involved as an opportunistic pathogen in cardiovascular infections. In this study, we investigated the functions of endopeptidase O (PepO) and a C3-degrading protease (CppA) in the systemic virulence of S. sanguini...

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Bibliographic Details
Main Authors: Lívia A. Alves, Hassan Naveed, Eduardo M. Franco, Maíra Terra Garcia, Victor A. Freitas, Juliana C. Junqueira, Débora C. Bastos, Thaís L. S. Araujo, Tsute Chen, Renata O. Mattos-Graner
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Streptococcus sanguinis
complement system
endothelial cell
Galleria mellonela
cardiovascular diseases
peptidase
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2239519
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https://www.tandfonline.com/doi/10.1080/21505594.2023.2239519

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