Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.

Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.

Contact-dependent growth inhibition (CDI) is a widespread form of inter-bacterial competition mediated by CdiA effector proteins. CdiA is presented on the inhibitor cell surface and delivers its toxic C-terminal region (CdiA-CT) into neighboring bacteria upon contact. Inhibitor cells also produce Cd...

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Main Authors: Tiffany M Halvorsen, Kaitlin A Schroeder, Allison M Jones, Disa Hammarlöf, David A Low, Sanna Koskiniemi, Christopher S Hayes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011494
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https://doi.org/10.1371/journal.pgen.1011494

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