CBL-mediated AQP1 ubiquitination aggravates kidney-yang deficiency syndrome by promoting lipid metabolism dysregulation

Abstract Objective Kidney-Yang Deficiency Syndrome (KYDS) is associated with lipid metabolism dysregulation. This study aimed to investigate the effect of casitas B-lineage lymphoma (CBL)-mediated aquaporin 1 (AQP1) ubiquitination on KYDS. Methods The KYDS rat model was induced via intraperitoneal i...

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Bibliographic Details
Main Authors: Yifei Wang, Jun Yuan, Wenfang He, Nan Yang, Lanjun Fu, Juan Jin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02743-9
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