Functional dissection of the TBK1 molecular network.

Functional dissection of the TBK1 molecular network.

TANK-binding kinase 1 (TBK1) and inducible IκB-kinase (IKK-i) are central regulators of type-I interferon induction. They are associated with three adaptor proteins called TANK, Sintbad (or TBKBP1) and NAP1 (or TBKBP2, AZI2) whose functional relationship to TBK1 and IKK-i is poorly understood. We pe...

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Main Authors: Adriana Goncalves, Tilmann Bürckstümmer, Evelyn Dixit, Ruth Scheicher, Maria W Górna, Evren Karayel, Cristina Sugar, Alexey Stukalov, Tiina Berg, Robert Kralovics, Melanie Planyavsky, Keiryn L Bennett, Jacques Colinge, Giulio Superti-Furga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023971&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023971&type=printable

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