Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena

Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena

Abstract Background INO80 and SWR1 are evolutionarily related ATP-dependent chromatin remodeling complexes that regulate the chromatin occupancy of the histone variant H2A.Z, playing critical roles in transcriptional regulation, genome replication, and DNA repair. While the H2A.Z-related functions o...

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Bibliographic Details
Main Authors: Jyoti Garg, Alejandro Saettone, Syed Nabeel-Shah, Steven Dang, Abdul Hadi Khalid, Jérémy Loehr, Alexandra Petrova, James D. Burns, Peter Karabatsos, Sherin Shibin, Suzanne Wahab, Sean D. Taverna, Jack F. Greenblatt, Jean-Philippe Lambert, Jeffrey Fillingham
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Epigenetics & Chromatin
Subjects:
Bromodomains
SWR1c
INO80c
H2A.Z
Chromatin remodeling
Transcription
Online Access:https://doi.org/10.1186/s13072-025-00614-5
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