Oral creatine-modified selenium-based hyaluronic acid nanogel mediated mitochondrial energy recovery to drive the treatment of inflammatory bowel disease

Oral creatine-modified selenium-based hyaluronic acid nanogel mediated mitochondrial energy recovery to drive the treatment of inflammatory bowel disease

Abstract The damnification of mitochondrion is often considered to be an important culprit of inflammatory bowel disease (IBD), however, there are fewer reports of mechanisms of mitochondria-mediated IBD treatment. Therefore, we first proposed to reboot mitochondrial energy metabolism to treat IBD b...

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Bibliographic Details
Main Authors: Manxiu Huai, Mingliang Pei, Jie Chen, Xiaoyan Duan, Yun Zhu, Fan Yang, Wensong Ge
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Mitochondrial repair
Nanogel
IBD treatment
ROS scavenging
Energy adjustment
Online Access:https://doi.org/10.1186/s12951-024-03007-0
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https://doi.org/10.1186/s12951-024-03007-0

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