Identification of TRPV1-Inhibitory Peptides from <i>Takifugu fasciatus</i> Skin Hydrolysate and Their Skin-Soothing Mechanisms

Identification of TRPV1-Inhibitory Peptides from <i>Takifugu fasciatus</i> Skin Hydrolysate and Their Skin-Soothing Mechanisms

Skin sensitivity is increasingly prevalent, necessitating new therapeutic agents. This study screened multifunctional peptides from <i>Takifugu fasciatus</i> skin for transient receptor potential vanilloid 1 (TRPV1)-inhibitory and anti-inflammatory activities and investigated their mecha...

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Bibliographic Details
Main Authors: Haiyan Tang, Bei Chen, Dong Zhang, Ruowen Wu, Kun Qiao, Kang Chen, Yongchang Su, Shuilin Cai, Min Xu, Shuji Liu, Zhiyu Liu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Marine Drugs
Subjects:
<i>Takifugu fasciatus</i>
TRPV1-inhibitory peptide
inflammatory response
bioactive peptide
NF-κB signaling
molecular docking network pharmacology
Online Access:https://www.mdpi.com/1660-3397/23/5/196
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