Identification of cancer-associated fibrolast subtypes and distinctive role of MFAP5 in CT-detected extramural venous invasion in gastric cancer

Identification of cancer-associated fibrolast subtypes and distinctive role of MFAP5 in CT-detected extramural venous invasion in gastric cancer

Extramural venous invasion (EMVI) detected by computed tomography has been identified as an independent risk factor for distant metastasis in patients with advanced gastric cancer (GC). Cancer-associated fibroblasts (CAFs) are critical for remodeling the tumor microenvironment in GCs. Here, we repor...

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Bibliographic Details
Main Authors: Bo Gao, Xinyi Gou, Caizhen Feng, Yinli Zhang, Huining Gu, Fan Chai, Yi Wang, Yingjiang Ye, Nan Hong, Guohua Hu, Boshi Sun, Jin Cheng, Hao Yang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Translational Oncology
Subjects:
Gastric cancer
Tumor microenviroment
MFAP5+ cancer-associated fibroblasts
Lactylation modification
Extramural venous invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003140
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