Antimicrobial, Antioxidant, and <i>α</i>-Glucosidase-Inhibitory Activities of Prenylated <i>p</i>-Hydroxybenzoic Acid Derivatives from <i>Oberonia ensiformis</i>
Seven previously undescribed prenylated <i>p</i>-hydroxybenzoic acid derivatives, oberoniaensiformisins A–G, were isolated from an EtOH extract of the whole plant <i>Oberonia ensiformis</i>. Their structures were determined through spectroscopic analyses (IR, NMR) and HRESIMS...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/10/2132 |
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| Summary: | Seven previously undescribed prenylated <i>p</i>-hydroxybenzoic acid derivatives, oberoniaensiformisins A–G, were isolated from an EtOH extract of the whole plant <i>Oberonia ensiformis</i>. Their structures were determined through spectroscopic analyses (IR, NMR) and HRESIMS analysis. The isolated compounds were tested for their antimicrobial, antioxidant, and <i>α</i>-glucosidase-inhibitory activity. Among them, compounds <b>6</b> and <b>12</b> exhibited potential antioxidant activity, while compounds <b>5</b>, <b>6</b>, <b>12</b>, <b>13</b>, and <b>15</b> showed varying degrees of <i>α</i>-glucosidase-inhibitory activity, with IC<sub>50</sub> values ranging from 34.03 to 106.10 μg/mL. |
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| ISSN: | 1420-3049 |