Sodium butyrate inhibits the expression of virulence factors in Vibrio cholerae by targeting ToxT protein

Sodium butyrate inhibits the expression of virulence factors in Vibrio cholerae by targeting ToxT protein

ABSTRACT Cholera, a diarrheal disease caused by the gram-negative bacterium Vibrio cholerae, remains a global health threat in developing countries due to its high transmissibility and increased antibiotic resistance. There is a pressing need for alternative strategies, with an emphasis on anti-viru...

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Main Authors: Sushmita Kundu, Suman Das, Priyanka Maitra, Prolay Halder, Hemanta Koley, Asish K. Mukhopadhyay, Shin-ichi Miyoshi, Shanta Dutta, Nabendu Sekhar Chatterjee, Sushmita Bhattacharya
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
Subjects:
sodium butyrate (SB)
inhibitor
pathogenesis
Vibrio cholerae
ctxAB
antimicrobial resistance
Online Access:https://journals.asm.org/doi/10.1128/msphere.00824-24
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