Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathways

Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathways

BackgroundMelanomas are caused by the malignant transformation of melanocytes. Numerous studies have demonstrated that the tyrosol components of salidroside inhibit tyrosinase activity. The PI3K/Akt/mTOR signaling pathway plays a crucial role in biological pigment synthesis. However, how salidroside...

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Bibliographic Details
Main Authors: Qi Ouyang, Shengye Tian, Hengyu Zhou, Ying Mao, Xiang Li, Feng Yan, Ailong Liu, Xiang Hu, Changqiao You, Jun He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
network pharmacology
salidroside
melanoma
oxidative stress
PI3K/Akt/mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1583580/full
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