Uncovering the multi-layer cis-regulatory landscape of rice via integrative nascent RNA analysis

Uncovering the multi-layer cis-regulatory landscape of rice via integrative nascent RNA analysis

Abstract Background Efforts to characterize regulatory elements in plant genomes traditionally rely on evolutionary conservation and chromatin accessibility. Recently, intergenic bi-directional nascent transcript has emerged as a putative hallmark of active enhancers. Here, we integrate these approa...

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Main Authors: Marina Goliasse, Aurore Johary, Adrian E. Platts, Fabian Ortner-Krause, Patrick P. Edger, Jae Young Choi, Michael D. Purugganan, Zoé Joly-Lopez
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Genome Biology
Subjects:
Gene regulation
cis-regulatory elements
Functional genomics
Transposable elements
Transcribed enhancers
Conserved noncoding sequences
Online Access:https://doi.org/10.1186/s13059-025-03715-2
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https://doi.org/10.1186/s13059-025-03715-2

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