Identifying representative sequences of protein families using submodular optimization

Identifying representative sequences of protein families using submodular optimization

Abstract Identifying representative sequences for groups of functionally similar proteins and enzymes poses significant computational challenges. In this study, we applied submodular optimization, a method effective in data summarization, to select representative sequences for thioesterase enzyme fa...

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Bibliographic Details
Main Authors: Ha Nguyen, Hung Nguyen, Phuong Nguyen, Anh N. Luu, David C. Cantu, Tin Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Protein analysis
Representative sequences
Submodular optimization
Online Access:https://doi.org/10.1038/s41598-025-85165-1
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https://doi.org/10.1038/s41598-025-85165-1

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