Comparison of efficacy of exosomes derived from human umbilical cord blood mesenchymal stem cells in treating mouse acute lung injury via different routes

Comparison of efficacy of exosomes derived from human umbilical cord blood mesenchymal stem cells in treating mouse acute lung injury via different routes

ObjectiveTo investigate the therapeutic efficacy of human umbilical cord blood mesenchymal stem cell-derived exosomes (hUCMSC-Exo) in a lipopolysaccharide (LPS)-induced acute lung injury (ALI) mouse model and compare the effects of different administration routes.MethodsAn ALI mouse model was establ...

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Bibliographic Details
Main Authors: Jing Chen, Shuang Liu, Jizhen Zou, Yi Wang, Haiyan Ge, Yi Hui, Siyuan Huang, Wei Li, Weilan Na, Xiaolan Huang, Lin Bai, Yiying Huang, Dong Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pediatrics
Subjects:
acute lung injury
acute respiratory distress syndrome
mesenchymal stem cells
exosomes
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1560915/full
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