The role of CAMP-dependent signaling systems in regulation of electrical and contractile properties of smooth muscles of the ureter in hypoxia in guinea pigs

The role of CAMP-dependent signaling systems in regulation of electrical and contractile properties of smooth muscles of the ureter in hypoxia in guinea pigs

Aim. To study the features of regulating the electrical activity and mechanical tension of smooth muscle cells (SMCs) of the guinea pig ureter as modulated by cyclic adenosine monophosphate (cAMP) in hypoxia. Materials and methods. The effects of isoprenaline (100 μM), forskolin (1 μM), 3-isobutyl-1...

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Main Authors: I. V. Kovalev, J. G. Birulina, S. V. Gusakova, A. V. Nosarev, L. V. Smagliy, I. V. Petrova, V. S. Rydchenko, A. A. Leshcheva, M. A. Medvedev, G. A. Suhanova, V.. N. Vasiliyev
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2019-08-01
Series:Бюллетень сибирской медицины
Subjects:
smooth muscles
cyclic adenosine monophosphate
adenylate cyclase
hypoxia
ion channels
Online Access:https://bulletin.ssmu.ru/jour/article/view/2311
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