Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study
BackgroundPost-dural puncture headache (PDPH) is still mostly regarded a minor complication after lumbar puncture. In the International Classification of Headache Disorders (ICHD)-3 headaches lasting longer than 14 days or persisting after epidural blood patch (EBP) are not even considered. We illus...
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1493303/full |
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| author | Luisa Mona Kraus Luisa Mona Kraus Levin Häni Levin Häni Amir El Rahal Ioannis Vasilikos Mateo Tomas Fariña Nuñez Mateo Tomas Fariña Nuñez Florian Volz Horst Urbach Niklas Lützen Christian Ulrich Jürgen Beck Christian Fung Christian Fung |
| author_facet | Luisa Mona Kraus Luisa Mona Kraus Levin Häni Levin Häni Amir El Rahal Ioannis Vasilikos Mateo Tomas Fariña Nuñez Mateo Tomas Fariña Nuñez Florian Volz Horst Urbach Niklas Lützen Christian Ulrich Jürgen Beck Christian Fung Christian Fung |
| author_sort | Luisa Mona Kraus |
| collection | DOAJ |
| description | BackgroundPost-dural puncture headache (PDPH) is still mostly regarded a minor complication after lumbar puncture. In the International Classification of Headache Disorders (ICHD)-3 headaches lasting longer than 14 days or persisting after epidural blood patch (EBP) are not even considered. We illustrate that there may be many patients with persisting headaches and a large disease burden.MethodsIn a retrospective, single center analysis from 04/2018 to 03/2022 we assessed patients with a dural puncture and orthostatic headache of >14 days duration, resistant to one or more EBPs. Socioeconomic factors and individual patient history were assessed by a specifically designed questionnaire.ResultsWe included 30 patients with a mean age of 36.4 (±10.6) years. The median duration of acute inpatient care was 31 (Interquartile ratio (IQR) = 32) days and of sick leave 381 (IQR = 666.3) days. Patients consulted a median of 5 (IQR = 6.5) different physicians/ institutions due to chronic post-dural puncture headache (cPDPH). All patients reported major negative impact of cPDPH on their social and work life.ConclusionDespite long hospitalizations and a profound impairment of social and work lives cPDPH was neglected and underrated in all patients. We conclude that cPDPH needs to be considered and might be an underreported, severe condition which requires further prospective studies. |
| format | Article |
| id | doaj-art-cb6d439bbc514d66b310379990377d8b |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj-art-cb6d439bbc514d66b310379990377d8b2024-11-29T08:40:11ZengFrontiers Media S.A.Frontiers in Neurology1664-22952024-11-011510.3389/fneur.2024.14933031493303Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort studyLuisa Mona Kraus0Luisa Mona Kraus1Levin Häni2Levin Häni3Amir El Rahal4Ioannis Vasilikos5Mateo Tomas Fariña Nuñez6Mateo Tomas Fariña Nuñez7Florian Volz8Horst Urbach9Niklas Lützen10Christian Ulrich11Jürgen Beck12Christian Fung13Christian Fung14Department of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, School of Medicine, Klinikum Rechts Der Isar, Technical University Munich, Munich, GermanyDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Inselspital Bern, University Hospital Bern, Bern, SwitzerlandDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanySpine Center, Schulthess Klinik, Zurich, SwitzerlandDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neuroradiology, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neuroradiology, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Lindenhofspital of Bern, Bern, SwitzerlandDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Lindenhofspital of Bern, Bern, SwitzerlandBackgroundPost-dural puncture headache (PDPH) is still mostly regarded a minor complication after lumbar puncture. In the International Classification of Headache Disorders (ICHD)-3 headaches lasting longer than 14 days or persisting after epidural blood patch (EBP) are not even considered. We illustrate that there may be many patients with persisting headaches and a large disease burden.MethodsIn a retrospective, single center analysis from 04/2018 to 03/2022 we assessed patients with a dural puncture and orthostatic headache of >14 days duration, resistant to one or more EBPs. Socioeconomic factors and individual patient history were assessed by a specifically designed questionnaire.ResultsWe included 30 patients with a mean age of 36.4 (±10.6) years. The median duration of acute inpatient care was 31 (Interquartile ratio (IQR) = 32) days and of sick leave 381 (IQR = 666.3) days. Patients consulted a median of 5 (IQR = 6.5) different physicians/ institutions due to chronic post-dural puncture headache (cPDPH). All patients reported major negative impact of cPDPH on their social and work life.ConclusionDespite long hospitalizations and a profound impairment of social and work lives cPDPH was neglected and underrated in all patients. We conclude that cPDPH needs to be considered and might be an underreported, severe condition which requires further prospective studies.https://www.frontiersin.org/articles/10.3389/fneur.2024.1493303/fullpostdural puncture headache (PDPH)chronic headachelumbar puncture (LP)peridural anesthesiasocioeconomial impact |
| spellingShingle | Luisa Mona Kraus Luisa Mona Kraus Levin Häni Levin Häni Amir El Rahal Ioannis Vasilikos Mateo Tomas Fariña Nuñez Mateo Tomas Fariña Nuñez Florian Volz Horst Urbach Niklas Lützen Christian Ulrich Jürgen Beck Christian Fung Christian Fung Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study Frontiers in Neurology postdural puncture headache (PDPH) chronic headache lumbar puncture (LP) peridural anesthesia socioeconomial impact |
| title | Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study |
| title_full | Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study |
| title_fullStr | Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study |
| title_full_unstemmed | Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study |
| title_short | Chronic post-dural puncture headache–a serious and underrated complication following lumbar puncture: a cohort study |
| title_sort | chronic post dural puncture headache a serious and underrated complication following lumbar puncture a cohort study |
| topic | postdural puncture headache (PDPH) chronic headache lumbar puncture (LP) peridural anesthesia socioeconomial impact |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1493303/full |
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