LXR pathway drives hormonal response intensity in polycystic ovary syndrome

LXR pathway drives hormonal response intensity in polycystic ovary syndrome

Abstract Gonadotropin injections used to stimulate oocyte production during assisted reproductive technology (ART) procedures are associated with the risk of an abnormal response in predisposed patients suffering polycystic ovary syndrome (PCOS). Liver X receptors (LXR) pathway has been identified a...

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Main Authors: Sarah Dallel, Manon Despalles, Margaux Tore, Yoan Renaud, Ayhan Kocer, Christelle Damon-Soubeyrand, Pierre Pouchin, Caroline Vachias, Katia Boutourlinsky, Céline Gonthier-Gueret, Angélique De Haze, Phelipe Sanchez, Jean-Christophe Pointud, Erwan Bouchareb, Marine Vialat, Aurélie Lagarde, Cristina Gulunga, Laure Chaput, Aurélie Vega, Florence Brugnon, Igor Tauveron, Amalia Trousson, Cyrille de Joussineau, Françoise Degoul, Laurent Morel, Jean Marc Lobaccaro, Salwan Maqdasy, Silvère Baron
Format: Article
Language:English
Published: Springer Nature 2025-05-01
Series:EMBO Molecular Medicine
Subjects:
Polycystic Ovary Syndrome
Granulosa Cells
Liver X Receptors
Hormonal Stimulation
Inflammasome
Online Access:https://doi.org/10.1038/s44321-025-00251-1
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