Role of glial cells in motor neuron degeneration in hereditary spastic paraplegias

This review provides a comprehensive overview of hereditary spastic paraplegias (HSPs) and summarizes the recent progress on the role of glial cells in the pathogenesis of HSPs. HSPs are a heterogeneous group of neurogenetic diseases characterized by axonal degeneration of cortical motor neurons, le...

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Bibliographic Details
Main Authors: Manaswini Vijayaraghavan, Sarvika Periyapalayam Murali, Gitika Thakur, Xue-Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1553658/full
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