Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis

Objective. Deficiencies in klotho are implicated in various kidney dysfunctions including diabetic nephropathy (DN) related to inflammatory responses. Klotho is closely related to inflammatory responses and is a potential target for ameliorating kidney failure. Pyroptosis, an inflammatory form of pr...

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Bibliographic Details
Main Authors: Jiaxin He, Jialin Cui, Yimin Shi, Tao Wang, Junyan Xin, Yimeng Li, Xiaomeng Shan, Zhiyao Zhu, Yanbin Gao
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2023/7423661
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