3D culture of neural progenitor cells in gelatin norbornene (GelNB) hydrogels: mechanical tuning and hypoxia characterization

3D culture of neural progenitor cells in gelatin norbornene (GelNB) hydrogels: mechanical tuning and hypoxia characterization

The development of physiologically relevant three-dimensional (3D) culture platforms for neural stem cell (NSC) cultivation is essential for advancing neuroscience research, disease modelling, and regenerative medicine. In this study, we introduce norbornene-functionalized gelatin (GelNB) hydrogels...

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Bibliographic Details
Main Authors: Sandra Dienemann, Ole Jacob Wohlenberg, Jan Georg Gerstenberger, Antonina Lavrentieva, Iliyana Pepelanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
gelatin-norbornene
hydrogels
IKVAV
neural stem cells
hypoxia
design of experiments
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1579580/full
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