Polymethoxyflavones extracted from Bauhinia championii alleviate LPS-induced acute lung injury by ameliorating endoplasmic reticulum stress

Polymethoxyflavones extracted from Bauhinia championii alleviate LPS-induced acute lung injury by ameliorating endoplasmic reticulum stress

BackgroundAcute lung injury (ALI), a critical respiratory condition, often escalates into acute respiratory distress syndrome, which is associated with significant morbidity and mortality. Bauhinia championii, a botanical drug used in traditional Chinese medicine, is reputed for its antioxidative an...

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Bibliographic Details
Main Authors: Yuanyuan Li, Xiaolan Yang, Wenjing Ye, Junsong Jing, Ranran Chen, Lianhao Wu, Zhenqiang You, Sheng Zhang, Jing Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
polymethoxyflavones
Bauhinia championii
acute lung injury
endoplasmic reticulum stress
network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1544916/full
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