Increase of solubility and transmembrane permeability of niclosamide from its mechanochemically synthesized solid dispersions
More than 4.5 billion people worldwide are affected by parasitic diseases, with helminth infections accounting for 99% of the total number. Niclosamide (NS) is a weakly acidic active pharmaceutical ingredient (API) used to treat helminth infections. However, the pharmaceutical use of pure niclosamid...
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| Main Authors: | Elizaveta S. Meteleva, Elizaveta A. Roenko, Nikolay E. Polyakov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina
2023-08-01
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| Series: | Chimica Techno Acta |
| Subjects: | |
| Online Access: | https://chimicatechnoacta.ru/article/view/6904 |
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