Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH‐MYCN transgenic mice

Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH‐MYCN transgenic mice

Abstract Neuroblastoma is a highly aggressive pediatric cancer with a poor prognosis, particularly in high‐risk (HR) cases characterized by MYCN amplification. The severe side effects associated with high‐dose chemotherapy further complicate treatment. Despite significant advancements in drug screen...

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Bibliographic Details
Main Authors: Yen‐Tzu Liao, Zhi‐Kai Yu, Yi‐Xun Huang, Kuan‐Hung Lin, Ching‐Te Kuo, Tsai‐Shan Yang, Pei‐Yi Wu, Chi‐Tai Yeh, Yen‐Lin Liu, Chien‐Chin Chen, Chiung‐Nien Chen, Wen‐Ming Hsu, Hsinyu Lee
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Bioengineering & Translational Medicine
Subjects:
BioNDP
chemotherapy
drug screening
neuroblastoma
synergy
TH‐MYCN mice
Online Access:https://doi.org/10.1002/btm2.70007
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