Effects of Pomegranate Seed Oil on Lower Extremity Ischemia-Reperfusion Damage: Insights into Oxidative Stress, Inflammation, and Cell Death

Effects of Pomegranate Seed Oil on Lower Extremity Ischemia-Reperfusion Damage: Insights into Oxidative Stress, Inflammation, and Cell Death

<i>Aim</i>: This study sought to clarify the therapeutic benefits and mechanisms of action of pomegranate seed oil (PSO) in instances of ischemia–reperfusion (IR) damage in the lower extremities. <i>Materials and Methods</i>: The sample size was determined, then 32 rats were...

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Bibliographic Details
Main Authors: Ümmü Gülşen Bozok, Aydan İremnur Ergörün, Ayşegül Küçük, Zeynep Yığman, Ali Doğan Dursun, Mustafa Arslan
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Medicina
Subjects:
apoptosis
inflammation
ischemia–reperfusion
lower extremity
NF-κB
oxidative stress
Online Access:https://www.mdpi.com/1648-9144/61/2/212
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