Hepatocytes derived from human induced pluripotent stem cells: Towards establishing an in vitro model for assessing population variability in hepatotoxicity testing
Interindividual differences in response to chemicals have been typically addressed through the use of a 10-fold default “uncertainty” factor. It was only recently that in vitro models emerged to quantitatively assess interindividual variability in the human population for specific chemicals. In the...
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| Main Authors: | Xiugong Gao, Rong Li, Kayla Campasino, Miranda R. Yourick, Yang Zhao, Robert L. Sprando, Jeffrey J. Yourick |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Current Research in Toxicology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666027X25000246 |
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