The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study
Conclusions: This study indicates that mutations in the HRR gene possess significant potential as a prognostic marker in OC. Our aim was to comprehensively explore how HRR gene mutations, including but not limited to BRCA, might influence the clinical course and survival of patients, shedding light...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/ogi/5578247 |
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| _version_ | 1850275735432855552 |
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| author | Shitong Zhan Feng Chen Lijuan Huang Lin Chen Haoyi Jia Shaofei Ma Min Tang Chongzhi Zhou Yanmin Chen Ye Yang |
| author_facet | Shitong Zhan Feng Chen Lijuan Huang Lin Chen Haoyi Jia Shaofei Ma Min Tang Chongzhi Zhou Yanmin Chen Ye Yang |
| author_sort | Shitong Zhan |
| collection | DOAJ |
| description | Conclusions: This study indicates that mutations in the HRR gene possess significant potential as a prognostic marker in OC. Our aim was to comprehensively explore how HRR gene mutations, including but not limited to BRCA, might influence the clinical course and survival of patients, shedding light on potential new avenues for personalized treatment strategies. |
| format | Article |
| id | doaj-art-aa2d73fcd20e409e8d3a532c2a66f88a |
| institution | OA Journals |
| issn | 1687-9597 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-aa2d73fcd20e409e8d3a532c2a66f88a2025-08-20T01:50:37ZengWileyObstetrics and Gynecology International1687-95972025-01-01202510.1155/ogi/5578247The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort StudyShitong Zhan0Feng Chen1Lijuan Huang2Lin Chen3Haoyi Jia4Shaofei Ma5Min Tang6Chongzhi Zhou7Yanmin Chen8Ye Yang9Obstetrics and Gynecology DepartmentObstetrics and Gynecology DepartmentObstetrics and Gynecology DepartmentObstetrics and Gynecology DepartmentObstetrics and Gynecology DepartmentPathology DepartmentSurgery DepartmentEducational DepartmentEducational DepartmentObstetrics and Gynecology DepartmentConclusions: This study indicates that mutations in the HRR gene possess significant potential as a prognostic marker in OC. Our aim was to comprehensively explore how HRR gene mutations, including but not limited to BRCA, might influence the clinical course and survival of patients, shedding light on potential new avenues for personalized treatment strategies.http://dx.doi.org/10.1155/ogi/5578247 |
| spellingShingle | Shitong Zhan Feng Chen Lijuan Huang Lin Chen Haoyi Jia Shaofei Ma Min Tang Chongzhi Zhou Yanmin Chen Ye Yang The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study Obstetrics and Gynecology International |
| title | The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study |
| title_full | The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study |
| title_fullStr | The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study |
| title_full_unstemmed | The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study |
| title_short | The Clinical Pathological Characteristics and Prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients: A Prospective Cohort Study |
| title_sort | clinical pathological characteristics and prognostic relevance of homologous recombination repair gene mutations in ovarian cancer patients a prospective cohort study |
| url | http://dx.doi.org/10.1155/ogi/5578247 |
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