Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol

Introduction Postoperative delirium is a serious complication occurring in 10.09%–51.28% of geriatric patients undergoing surgery for hip fractures. Delirium has resulted in poorer functional recovery, increased readmission rates, repeat surgeries and elevated mortality. Perioperative music listenin...

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Main Authors: Ling Wang, Lin-Yu Chao, Chun-Chih Lin, Hsing-Ju Lu, Jiun-Liang Chen, Han-Chang Ku
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/8/e095492.full
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author Ling Wang
Lin-Yu Chao
Chun-Chih Lin
Hsing-Ju Lu
Jiun-Liang Chen
Han-Chang Ku
author_facet Ling Wang
Lin-Yu Chao
Chun-Chih Lin
Hsing-Ju Lu
Jiun-Liang Chen
Han-Chang Ku
author_sort Ling Wang
collection DOAJ
description Introduction Postoperative delirium is a serious complication occurring in 10.09%–51.28% of geriatric patients undergoing surgery for hip fractures. Delirium has resulted in poorer functional recovery, increased readmission rates, repeat surgeries and elevated mortality. Perioperative music listening is a promising non-pharmacological intervention with beneficial effects on delirium. This trial aims to evaluate the effect of perioperative music listening on postoperative delirium in patients with femur fracture undergoing surgery.Methods and analysis The music listening on clinical outcome after hip fracture operations study is an investigator-initiated, randomised controlled, clinical trial. 102 patients with femur fracture meeting eligibility criteria will be randomised to the music listening intervention or control group with concealed allocation. The perioperative music intervention consists of preselected lists totalling 4 hours of music (classical, jazz and pop). The primary outcome is postoperative delirium rate. Secondary outcome measures include pain score and opioid medication requirement, postoperative complications, hospital length of stay, 14-day readmission rate and 30-day mortality. A 90-day follow-up will be performed in order to assess readmission rate and mortality rate. Data will be analysed according to an intention-to-treat principle.Ethics and dissemination The study protocol was approved by the Research Ethics Committee of Ditmanson Medical Foundation of Chia-Yi Christian Hospital (IRB2023084). The trial will be carried out following the Declaration of Helsinki principles and Good Clinical Practice guidelines. Research data will be reported following Consolidated Standards of Reporting Trials guidelines and study results will be published in a peer-reviewed journal and presented at scientific conferences. Data availability statement: data generated by this study will be made available on reasonable request. A data sharing plan has been submitted to ClinicalTrials.gov in compliance with ICMJE (International Committee of Medical Journal Editors) and BMJ Open data policies.Trial registration number NCT06209788.
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spelling doaj-art-a9af41b32c8e4ea6b0bcdec87058ac472025-08-20T03:41:31ZengBMJ Publishing GroupBMJ Open2044-60552025-08-0115810.1136/bmjopen-2024-095492Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocolLing Wang0Lin-Yu Chao1Chun-Chih Lin2Hsing-Ju Lu3Jiun-Liang Chen4Han-Chang Ku5Fantastique Philharmonic Association for Music Education, Tainan City, TaiwanDitmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, TaiwanNursing, Chang Gung University of Science and Technology—Chiayi Campus, Puzi City, TaiwanDepartment of Nursing, Chiayi Chang Gung Memorial Hospital, Puzi City, TaiwanDepartment of Orthopaedic Surgery, Chiayi Chang Gung Memorial Hospital, Puzi City, TaiwanDepartment of Nursing, Chang Gung University of Science and Technology—Chiayi Campus, Puzi City, TaiwanIntroduction Postoperative delirium is a serious complication occurring in 10.09%–51.28% of geriatric patients undergoing surgery for hip fractures. Delirium has resulted in poorer functional recovery, increased readmission rates, repeat surgeries and elevated mortality. Perioperative music listening is a promising non-pharmacological intervention with beneficial effects on delirium. This trial aims to evaluate the effect of perioperative music listening on postoperative delirium in patients with femur fracture undergoing surgery.Methods and analysis The music listening on clinical outcome after hip fracture operations study is an investigator-initiated, randomised controlled, clinical trial. 102 patients with femur fracture meeting eligibility criteria will be randomised to the music listening intervention or control group with concealed allocation. The perioperative music intervention consists of preselected lists totalling 4 hours of music (classical, jazz and pop). The primary outcome is postoperative delirium rate. Secondary outcome measures include pain score and opioid medication requirement, postoperative complications, hospital length of stay, 14-day readmission rate and 30-day mortality. A 90-day follow-up will be performed in order to assess readmission rate and mortality rate. Data will be analysed according to an intention-to-treat principle.Ethics and dissemination The study protocol was approved by the Research Ethics Committee of Ditmanson Medical Foundation of Chia-Yi Christian Hospital (IRB2023084). The trial will be carried out following the Declaration of Helsinki principles and Good Clinical Practice guidelines. Research data will be reported following Consolidated Standards of Reporting Trials guidelines and study results will be published in a peer-reviewed journal and presented at scientific conferences. Data availability statement: data generated by this study will be made available on reasonable request. A data sharing plan has been submitted to ClinicalTrials.gov in compliance with ICMJE (International Committee of Medical Journal Editors) and BMJ Open data policies.Trial registration number NCT06209788.https://bmjopen.bmj.com/content/15/8/e095492.full
spellingShingle Ling Wang
Lin-Yu Chao
Chun-Chih Lin
Hsing-Ju Lu
Jiun-Liang Chen
Han-Chang Ku
Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
BMJ Open
title Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
title_full Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
title_fullStr Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
title_full_unstemmed Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
title_short Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
title_sort effect of music listening on delirium after hip fracture operations mldhfo in a regional hospital in taiwan a randomised controlled trial protocol
url https://bmjopen.bmj.com/content/15/8/e095492.full
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