P30 | NEW INSIGHT IN THE IN VITRO-GENERATION OF INSULIN-PRODUCING CELLS: VAV1 AS A REGULATOR OF PDX1 AND MIR-375 LEVELS DURING DIFFERENTIATION OF HIPSCS INTO Β-CELLS

Type 1 diabetes (T1D) is a chronic autoimmune disorder marked by the destruction of pancreatic β-cells, leading to impaired insulin production1. Transplantation of insulin-producing cells (IPCs) derived from human induced pluripotent stem cells (hiPSCs) represents a promising therapeutic strategy t...

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Bibliographic Details
Format: Article
Language:English
Published: PAGEPress Publications 2025-08-01
Series:European Journal of Histochemistry
Subjects:
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Online Access:https://www.ejh.it/ejh/article/view/4350
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