Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?

Several authors have advanced the idea that psychedelics such as psilocybin might be effective means for achieving moral bioenhancement (MBE). Here, I discuss some reservations on this assertion from both neuropharmacological and bioethical perspectives, and surmised that there is little, if any, go...

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Main Author: Bor Luen Tang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Psychoactives
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Online Access:https://www.mdpi.com/2813-1851/4/1/5
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author Bor Luen Tang
author_facet Bor Luen Tang
author_sort Bor Luen Tang
collection DOAJ
description Several authors have advanced the idea that psychedelics such as psilocybin might be effective means for achieving moral bioenhancement (MBE). Here, I discuss some reservations on this assertion from both neuropharmacological and bioethical perspectives, and surmised that there is little, if any, good justification for such a claim. The indication of psychedelics for MBE is undermined by their hallucinogenic properties and the risk of adverse psychosis. There is also a lack of sound bioethical basis for using psychedelics to enhance morality. Based on our current understanding, the use of psychedelics specifically for MBE in healthy individuals would violate the ethical principle of non-maleficence. Unless there is unequivocal demonstration that psychedelics could enhance morality, or that new non-hallucinogenic derivatives become available, an indication for psychedelics in MBE would be untenable.
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spelling doaj-art-a1aa239d225a490fb7d060ecb87d2a532025-08-20T02:43:06ZengMDPI AGPsychoactives2813-18512025-02-0141510.3390/psychoactives4010005Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?Bor Luen Tang0Department of Biochemistry, National University of Singapore, MD7, 8 Medical Drive, Singapore 117596, SingaporeSeveral authors have advanced the idea that psychedelics such as psilocybin might be effective means for achieving moral bioenhancement (MBE). Here, I discuss some reservations on this assertion from both neuropharmacological and bioethical perspectives, and surmised that there is little, if any, good justification for such a claim. The indication of psychedelics for MBE is undermined by their hallucinogenic properties and the risk of adverse psychosis. There is also a lack of sound bioethical basis for using psychedelics to enhance morality. Based on our current understanding, the use of psychedelics specifically for MBE in healthy individuals would violate the ethical principle of non-maleficence. Unless there is unequivocal demonstration that psychedelics could enhance morality, or that new non-hallucinogenic derivatives become available, an indication for psychedelics in MBE would be untenable.https://www.mdpi.com/2813-1851/4/1/5moral bioenhancementpsilocybinpsychedelicsnon-maleficence
spellingShingle Bor Luen Tang
Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
Psychoactives
moral bioenhancement
psilocybin
psychedelics
non-maleficence
title Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
title_full Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
title_fullStr Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
title_full_unstemmed Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
title_short Psychedelics for Moral Bioenhancement in Healthy Individuals—A Violation of the Non-Maleficence Principle?
title_sort psychedelics for moral bioenhancement in healthy individuals a violation of the non maleficence principle
topic moral bioenhancement
psilocybin
psychedelics
non-maleficence
url https://www.mdpi.com/2813-1851/4/1/5
work_keys_str_mv AT borluentang psychedelicsformoralbioenhancementinhealthyindividualsaviolationofthenonmaleficenceprinciple