Magnolol and honokiol: potential lead compounds for the new drug discovery in treating autoimmune diseases

Magnolol and honokiol: potential lead compounds for the new drug discovery in treating autoimmune diseases

Saved in:

Bibliographic Details
Main Authors:	Xian Lin, Jian Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Pharmacology
Subjects:	magnolol honokiol autoimmune diseases rheumatoid arthritis lead compound
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1578971/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Repurposing old natural compounds to target new pathogens: honokiol and magnolol against Candida auris
by: Mihai Mares, et al.
Published: (2024-12-01)

Polymer-Free Electrospinning of β-Cyclodextrin–Oligolactide for Magnolol and Honokiol Pharmaceutical Formulations
by: Diana-Andreea Blaj, et al.
Published: (2025-01-01)

Inhibition of Bovine Enterovirus Infection by Magnolol via Modulating the Gut Microbiota in Mice
by: Junying Hu, et al.
Published: (2025-05-01)

Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy
by: Jian Wu, et al.
Published: (2024-12-01)

Enhanced penetration and biofilm eradication by sophorolipid micelles encapsulating Honokiol: a comprehensive solution for biofilm-associated lung infections
by: Shiyu Lin, et al.
Published: (2025-02-01)

Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
by: Ahsas Goyal, et al.
Published: (2025-03-01)

Potential role of magnolol: A comprehensive review on its efficacy in managing neurological disorders
by: Nasrin Sultana, et al.
Published: (2025-06-01)

Magnolol induces cell death through PI3K/Akt‐mediated epigenetic modifications boosting treatment of BRAF‐ and NRAS‐mutant melanoma
by: Abdullah Al Emran, et al.
Published: (2019-03-01)

Magnolol and its semi-synthetic derivatives: a comprehensive review of anti-cancer mechanisms, pharmacokinetics, and future therapeutic potential
by: Asmita Rayamajhi, et al.
Published: (2025-05-01)

Magnolol Inhibits High Fructose-Induced Podocyte Inflammation via Downregulation of TKFC/Sp1/HDAC4/Notch1 Activation
by: Ziang Zhou, et al.
Published: (2024-10-01)

Honokiol protects against diabetic retinal microvascular injury via sirtuin 3-mediated mitochondrial fusion
by: Jiemei Shi, et al.
Published: (2024-10-01)

Evaluation of the therapeutic effects of the topical and systemic forms of Honokiol in 5-fluorouracil-induced oral mucositis model in rats
by: Ayse Ozcan Kucuk, et al.
Published: (2025-06-01)

Honokiol ameliorates reserpine-induced fibromyalgia through antioxidant, anti-inflammatory, neurotrophic, and anti-apoptotic mechanisms
by: Suzan A. Khodir, et al.
Published: (2025-07-01)

Network Pharmacology, Molecular Docking, and Molecular Dynamics Analysis of Honokiol against Triple-negative Breast Cancer
by: Hassan H. Alhassan
Published: (2024-12-01)

Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation
by: Lian Zeng, et al.
Published: (2025-06-01)

Subinhibitory concentrations of Honokiol reduce α-Hemolysin (Hla) secretion by Staphylococcus aureus and the Hla-induced inflammatory response by inactivating the NLRP3 inflammasome
by: Na Guo, et al.
Published: (2019-01-01)

Honokiol induces apoptosis and autophagy in dexamethasone-resistant T-acute lymphoblastic leukemia CEM-C1 cells
by: Yang Liu, et al.
Published: (2024-12-01)

Microbial players in autoimmunity: multicentric analysis of the association between Mycoplasma hominis serostatus and rheumatoid arthritis
by: G. L. Erre, et al.
Published: (2025-03-01)

Unusual presentation of rheumatoid arthritis in a 106‐year‐old woman: A rare case report
by: Ali ALQazzaz, et al.
Published: (2023-03-01)

Osthole regulates N6‐methyladenosine‐modified TGM2 to inhibit the progression of rheumatoid arthritis and associated interstitial lung disease
by: Xian Lin, et al.
Published: (2023-04-01)

Rheumatic autoimmune disease in relation to post-traumatic stress disease and traumatic brain injury
by: R. Hal Scofield, et al.
Published: (2025-04-01)

Herpes Zoster Reactivation Following COVID-19 and the Risk of Renal, Infectious, and Autoimmune Complications: A Global Propensity-Matched Cohort Study
by: Ming-Hung Chien, et al.
Published: (2025-07-01)

Exploring the role of APRIL in autoimmunity: implications for therapeutic targeting in systemic lupus erythematosus, rheumatoid arthritis, and Sjögren’s syndrome
by: Anastasia V. Poznyak, et al.
Published: (2025-08-01)

An atypical multiple autoimmune syndrome: A case report including myocarditis
by: Ikram Tahani, MD, et al.
Published: (2025-06-01)

Extra‐articular involvement of rheumatoid arthritis in three seropositive patients in the absence of initial joint involvement
by: Razvan M. Chirila, et al.
Published: (2021-12-01)

Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017)
by: Hanna Lee, et al.
Published: (2024-11-01)

Multi-target drug discovery for rheumatoid arthritis: a comprehensive computational approach using bioactive compounds
by: Pegah Mansouri, et al.
Published: (2025-07-01)

Vitamin, antioxidant and micronutrient supplementation and the risk of developing incident autoimmune diseases: a systematic review and meta-analysis
by: Chen Ee Low, et al.
Published: (2024-12-01)

T-Follicular Helper Cells and Their Role in Autoimmune Diseases
by: Michalis Christodoulou, et al.
Published: (2025-04-01)

Sex-specific and regional differences in the prevalence of diagnosed autoimmune diseases in Germany, 2022
by: Manas K. Akmatov, et al.
Published: (2025-03-01)

Chikungunya Fever and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
by: José Kennedy Amaral, et al.
Published: (2025-02-01)

MAST CELLS ARE KEY PARTICIPANTS IN THE PATHOGENESIS OF IMMUNOINFLAMMATORY DISEASES
by: E. O. Baglay, et al.
Published: (2015-04-01)

Unveiling malignancy patterns among rheumatology patients: Insights from a retrospective study
by: Senem Tekeoğlu
Published: (2025-03-01)

The Challenging Management of Rheumatoid Arthritis Overlapping With Graves' Disease in a Young Male: A Case Report
by: Suaad Hamsho, et al.
Published: (2025-06-01)

Pediatric infections in the first year of life following maternal biologic exposure for autoimmune disorder treatment: A systematic review
by: Renee Gabrielle Fajardo, et al.
Published: (2025-07-01)

The association between exposure to brominated flame retardants (BFRs) and arthritis, osteoarthritis, and rheumatoid arthritis: a cross-sectional study
by: Yuxuan Wang, et al.
Published: (2025-07-01)

Vitamins improve the effect of heavy metal exposure in arthritis after hysterectomy
by: Binkai Xu, et al.
Published: (2025-08-01)

Exploring the Causal Link Between Autoimmune Diseases and Pulmonary Arterial Hypertension: A Bidirectional Mendelian Randomization Study
by: Chao Ma, et al.
Published: (2025-07-01)

Detection of Toxoplasma gondii IgM in a Sample of Rheumatoid Arthritis Patients Receiving Biological Therapy
by: Ikram Khazal Qasim Al- hasso, et al.
Published: (2025-04-01)

Relevance of elevated microparticles in peripheral blood and synovial fluid of patients with rheumatoid arthritis
by: Benita N R Michael, et al.
Published: (2018-01-01)