CD11b Expression Level Measurement to Distinguish Asthma Phenotype in Pediatric Patients

Background Inflammation is involved in asthma pathogenesis. Based on the majority of inflammatory cells found in blood samples, asthma is divided into neutrophilic and eosinophilic phenotype. CD11b is a leukocyte surface antigen that is involved in the inflammation process. However, the i...

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Bibliographic Details
Main Authors: Tien Budi Febriani, Soeroyo Mahfudz, Emi Azmi Choironi, Ninda Devita, Adika Zhulhi Arjana, Muhammad Nur Imansyah
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2025-01-01
Series:Avicenna Journal of Medicine
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1802666
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Summary:Background Inflammation is involved in asthma pathogenesis. Based on the majority of inflammatory cells found in blood samples, asthma is divided into neutrophilic and eosinophilic phenotype. CD11b is a leukocyte surface antigen that is involved in the inflammation process. However, the immunologic response mechanism in asthma phenotypes, especially in pediatric population, is still unclear. The aim of this study was to find the difference of CD11b expression in neutrophilic and eosinophilic phenotype of asthma in pediatric patients.
ISSN:2231-0770
2249-4464