Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)

Abstract Seven in absentia proteins, which contain a conserved SINA domain, are involved in regulating various aspects of wheat (Triticum aestivum L.) growth and development, especially in response to environmental stresses. However, it is unclear whether TaSINA family members are involved in regula...

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Main Authors: Tao Chen, Yongping Miao, Fanli Jing, Weidong Gao, Yanyan Zhang, Long Zhang, Peipei Zhang, Lijian Guo, Delong Yang
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:The Plant Genome
Online Access:https://doi.org/10.1002/tpg2.20480
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author Tao Chen
Yongping Miao
Fanli Jing
Weidong Gao
Yanyan Zhang
Long Zhang
Peipei Zhang
Lijian Guo
Delong Yang
author_facet Tao Chen
Yongping Miao
Fanli Jing
Weidong Gao
Yanyan Zhang
Long Zhang
Peipei Zhang
Lijian Guo
Delong Yang
author_sort Tao Chen
collection DOAJ
description Abstract Seven in absentia proteins, which contain a conserved SINA domain, are involved in regulating various aspects of wheat (Triticum aestivum L.) growth and development, especially in response to environmental stresses. However, it is unclear whether TaSINA family members are involved in regulating grain development until now. In this study, the expression pattern, genomic polymorphism, and relationship with grain‐related traits were analyzed for all TaSINA members. Most of the TaSINA genes identified showed higher expression levels in young wheat spikes or grains than other organs. The genomic polymorphism analysis revealed that at least 62 TaSINA genes had different haplotypes, where the haplotypes of five genes were significantly correlated with grain‐related traits. Kompetitive allele‐specific PCR markers were developed to confirm the single nucleotide polymorphisms in TaSINA101 and TaSINA109 among the five selected genes in a set of 292 wheat accessions. The TaSINA101‐Hap II and TaSINA109‐Hap II haplotypes had higher grain weight and width compared to TaSINA101‐Hap I and TaSINA109‐Hap I in at least three environments, respectively. The qRT‐PCR assays revealed that TaSINA101 was highly expressed in the palea shell, seed coat, and embryo in young wheat grains. The TaSINA101 protein was unevenly distributed in the nucleus when transiently expressed in the protoplast of wheat. Three homozygous TaSINA101 transgenic lines in rice (Oryza sativa L.) showed higher grain weight and size compared to the wild type. These findings provide valuable insight into the biological function and elite haplotype of TaSINA family genes in wheat grain development at a genomic‐wide level.
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publishDate 2024-09-01
publisher Wiley
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series The Plant Genome
spelling doaj-art-9f1e4e2c3a7b44939f54bc0e8a68ef7c2024-11-17T09:46:07ZengWileyThe Plant Genome1940-33722024-09-01173n/an/a10.1002/tpg2.20480Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)Tao Chen0Yongping Miao1Fanli Jing2Weidong Gao3Yanyan Zhang4Long Zhang5Peipei Zhang6Lijian Guo7Delong Yang8State Key Laboratory of Aridland Crop Science Gansu Agricultural University Lanzhou ChinaCollege of Life Science and Technology Gansu Agricultural University Lanzhou ChinaCollege of Life Science and Technology Gansu Agricultural University Lanzhou ChinaCollege of Life Science and Technology Gansu Agricultural University Lanzhou ChinaCollege of Life Science and Technology Gansu Agricultural University Lanzhou ChinaCollege of Life Science and Technology Gansu Agricultural University Lanzhou ChinaState Key Laboratory of Aridland Crop Science Gansu Agricultural University Lanzhou ChinaState Key Laboratory of Aridland Crop Science Gansu Agricultural University Lanzhou ChinaState Key Laboratory of Aridland Crop Science Gansu Agricultural University Lanzhou ChinaAbstract Seven in absentia proteins, which contain a conserved SINA domain, are involved in regulating various aspects of wheat (Triticum aestivum L.) growth and development, especially in response to environmental stresses. However, it is unclear whether TaSINA family members are involved in regulating grain development until now. In this study, the expression pattern, genomic polymorphism, and relationship with grain‐related traits were analyzed for all TaSINA members. Most of the TaSINA genes identified showed higher expression levels in young wheat spikes or grains than other organs. The genomic polymorphism analysis revealed that at least 62 TaSINA genes had different haplotypes, where the haplotypes of five genes were significantly correlated with grain‐related traits. Kompetitive allele‐specific PCR markers were developed to confirm the single nucleotide polymorphisms in TaSINA101 and TaSINA109 among the five selected genes in a set of 292 wheat accessions. The TaSINA101‐Hap II and TaSINA109‐Hap II haplotypes had higher grain weight and width compared to TaSINA101‐Hap I and TaSINA109‐Hap I in at least three environments, respectively. The qRT‐PCR assays revealed that TaSINA101 was highly expressed in the palea shell, seed coat, and embryo in young wheat grains. The TaSINA101 protein was unevenly distributed in the nucleus when transiently expressed in the protoplast of wheat. Three homozygous TaSINA101 transgenic lines in rice (Oryza sativa L.) showed higher grain weight and size compared to the wild type. These findings provide valuable insight into the biological function and elite haplotype of TaSINA family genes in wheat grain development at a genomic‐wide level.https://doi.org/10.1002/tpg2.20480
spellingShingle Tao Chen
Yongping Miao
Fanli Jing
Weidong Gao
Yanyan Zhang
Long Zhang
Peipei Zhang
Lijian Guo
Delong Yang
Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
The Plant Genome
title Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
title_full Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
title_fullStr Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
title_full_unstemmed Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
title_short Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)
title_sort genomic wide analysis reveals seven in absentia genes regulating grain development in wheat triticum aestivum l
url https://doi.org/10.1002/tpg2.20480
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