MATES: a deep learning-based model for locus-specific quantification of transposable elements in single cell

Abstract Transposable elements (TEs) are crucial for genetic diversity and gene regulation. Current single-cell quantification methods often align multi-mapping reads to either ‘best-mapped’ or ‘random-mapped’ locations and categorize them at the subfamily levels, overlooking the biological necessit...

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Bibliographic Details
Main Authors: Ruohan Wang, Yumin Zheng, Zijian Zhang, Kailu Song, Erxi Wu, Xiaopeng Zhu, Tao P. Wu, Jun Ding
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53114-7
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