The Potential of Metabolomics in Colorectal Cancer Prognosis

Colorectal cancer (CRC) is one of the most common cancers worldwide, posing a serious threat to human health. Metabolic reprogramming represents a critical feature in the process of tumor development and progression, encompassing alterations in sugar metabolism, lipid metabolism, amino acid metaboli...

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Main Authors: Chengqu Fu, Xinyi Liu, Le Wang, Dong Hang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/14/12/708
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author Chengqu Fu
Xinyi Liu
Le Wang
Dong Hang
author_facet Chengqu Fu
Xinyi Liu
Le Wang
Dong Hang
author_sort Chengqu Fu
collection DOAJ
description Colorectal cancer (CRC) is one of the most common cancers worldwide, posing a serious threat to human health. Metabolic reprogramming represents a critical feature in the process of tumor development and progression, encompassing alterations in sugar metabolism, lipid metabolism, amino acid metabolism, and other pathways. Metabolites hold promise as innovative prognostic biomarkers for cancer patients, which is crucial for targeted follow-up care and interventions. This review aims to provide an overview of the progress in research on metabolic biomarkers for predicting the prognosis of CRC. We also discuss the future trends and challenges in this area.
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spelling doaj-art-9bc0f9eaae5447dbbb27afbaaf9011012024-12-27T14:39:38ZengMDPI AGMetabolites2218-19892024-12-01141270810.3390/metabo14120708The Potential of Metabolomics in Colorectal Cancer PrognosisChengqu Fu0Xinyi Liu1Le Wang2Dong Hang3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative, Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, ChinaDepartment of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative, Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, ChinaDepartment of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, ChinaDepartment of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative, Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, ChinaColorectal cancer (CRC) is one of the most common cancers worldwide, posing a serious threat to human health. Metabolic reprogramming represents a critical feature in the process of tumor development and progression, encompassing alterations in sugar metabolism, lipid metabolism, amino acid metabolism, and other pathways. Metabolites hold promise as innovative prognostic biomarkers for cancer patients, which is crucial for targeted follow-up care and interventions. This review aims to provide an overview of the progress in research on metabolic biomarkers for predicting the prognosis of CRC. We also discuss the future trends and challenges in this area.https://www.mdpi.com/2218-1989/14/12/708colorectal cancerbiomarkermetabolomicsprognosis
spellingShingle Chengqu Fu
Xinyi Liu
Le Wang
Dong Hang
The Potential of Metabolomics in Colorectal Cancer Prognosis
Metabolites
colorectal cancer
biomarker
metabolomics
prognosis
title The Potential of Metabolomics in Colorectal Cancer Prognosis
title_full The Potential of Metabolomics in Colorectal Cancer Prognosis
title_fullStr The Potential of Metabolomics in Colorectal Cancer Prognosis
title_full_unstemmed The Potential of Metabolomics in Colorectal Cancer Prognosis
title_short The Potential of Metabolomics in Colorectal Cancer Prognosis
title_sort potential of metabolomics in colorectal cancer prognosis
topic colorectal cancer
biomarker
metabolomics
prognosis
url https://www.mdpi.com/2218-1989/14/12/708
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