Role of PD-1/PD-L1 signaling axis in oncogenesis and its targeting by bioactive natural compounds for cancer immunotherapy

Role of PD-1/PD-L1 signaling axis in oncogenesis and its targeting by bioactive natural compounds for cancer immunotherapy

Abstract Cancer is a global health problem and one of the leading causes of mortality. Immune checkpoint inhibitors have revolutionized the field of oncology, emerging as a powerful treatment strategy. A key pathway that has garnered considerable attention is programmed cell death-1 (PD-1)/programme...

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Bibliographic Details
Main Authors: Yogesh Godiyal, Drishti Maheshwari, Hiroaki Taniguchi, Shweta S. Zinzuwadia, Yanelys Morera-Díaz, Devesh Tewari, Anupam Bishayee
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Military Medical Research
Subjects:
Cancer
PD-1/PD-L1
Crosstalk
Natural compounds
Therapeutic targets
Online Access:https://doi.org/10.1186/s40779-024-00586-9
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