Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis
Toxic epidermal necrolysis (TEN) is associated with a significant mortality of 30–50% and long-term sequelae. Treatment includes early admission to a burn unit, where management with precise fluid, electrolyte, protein, and energy supplementation, moderate mechanical ventilation, and expert wound ca...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2011-09-01
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| Series: | Indian Journal of Plastic Surgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699520 |
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| author | S. Bhattacharya H. N. Tripathi V. Gupta Bharti Nigam A. Khanna |
| author_facet | S. Bhattacharya H. N. Tripathi V. Gupta Bharti Nigam A. Khanna |
| author_sort | S. Bhattacharya |
| collection | DOAJ |
| description | Toxic epidermal necrolysis (TEN) is associated with a significant mortality of 30–50% and long-term sequelae. Treatment includes early admission to a burn unit, where management with precise fluid, electrolyte, protein, and energy supplementation, moderate mechanical ventilation, and expert wound care can be provided. Specific treatment with immunosuppressive drugs or immunoglobulins did not show an improved outcome in most studies and remains controversial. We have treated the cutaneous lesions of seven patients of TEN with collagen sheet dressings and have found a significant reduction in morbidity. The sheets are a one-time dressing, easy to apply and they reduce fluid loss, prevent infection, reduce pain, avoid repeated dressings and gradually peal off as the underlying lesions heal. |
| format | Article |
| id | doaj-art-9997eebcf2b942e6a43df304e6d74e3c |
| institution | DOAJ |
| issn | 0970-0358 1998-376X |
| language | English |
| publishDate | 2011-09-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj-art-9997eebcf2b942e6a43df304e6d74e3c2025-08-20T03:18:53ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03581998-376X2011-09-01440347447710.1055/s-0039-1699520Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysisS. Bhattacharya0H. N. Tripathi1V. Gupta2Bharti Nigam3A. Khanna4Department of Plastic Surgery, Sahara Hospital and Ajanta Hospital, Lucknow, Uttar Pradesh, IndiaDepartment of Internal Medicine, Lucknow, Uttar Pradesh, IndiaDepartment of Dermatology and Sahara Hospital, Lucknow, Uttar Pradesh, IndiaDepartment of Ophthalmology, Sahara Hospital, Lucknow, Uttar Pradesh, IndiaDepartment of Surgery, Ajanta Hospital, Lucknow, Uttar Pradesh, IndiaToxic epidermal necrolysis (TEN) is associated with a significant mortality of 30–50% and long-term sequelae. Treatment includes early admission to a burn unit, where management with precise fluid, electrolyte, protein, and energy supplementation, moderate mechanical ventilation, and expert wound care can be provided. Specific treatment with immunosuppressive drugs or immunoglobulins did not show an improved outcome in most studies and remains controversial. We have treated the cutaneous lesions of seven patients of TEN with collagen sheet dressings and have found a significant reduction in morbidity. The sheets are a one-time dressing, easy to apply and they reduce fluid loss, prevent infection, reduce pain, avoid repeated dressings and gradually peal off as the underlying lesions heal.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699520toxic epidermal necrolysisstevens johnson's syndromecollagen sheet |
| spellingShingle | S. Bhattacharya H. N. Tripathi V. Gupta Bharti Nigam A. Khanna Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis Indian Journal of Plastic Surgery toxic epidermal necrolysis stevens johnson's syndrome collagen sheet |
| title | Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| title_full | Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| title_fullStr | Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| title_full_unstemmed | Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| title_short | Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| title_sort | collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis |
| topic | toxic epidermal necrolysis stevens johnson's syndrome collagen sheet |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699520 |
| work_keys_str_mv | AT sbhattacharya collagensheetdressingsforcutaneouslesionsoftoxicepidermalnecrolysis AT hntripathi collagensheetdressingsforcutaneouslesionsoftoxicepidermalnecrolysis AT vgupta collagensheetdressingsforcutaneouslesionsoftoxicepidermalnecrolysis AT bhartinigam collagensheetdressingsforcutaneouslesionsoftoxicepidermalnecrolysis AT akhanna collagensheetdressingsforcutaneouslesionsoftoxicepidermalnecrolysis |