Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine

Migraine is a highly prevalent neurological disorder and has been the second leading cause of disability worldwide for many years. The pathophysiology of migraines is complicated, and most available medications have unpleasant side effects. Therefore, it is essential to understand the mechanism of m...

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Main Authors: Mei-Rong Wu, Yi Ou, Rui Han, Tian-Tian Li, Ming-Yan Wei, Hong Guo, Yao-Dong Miao, Kai Wang, Han Zhang, Lin Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:World Journal of Traditional Chinese Medicine
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Online Access:https://journals.lww.com/10.4103/wjtcm.wjtcm_90_24
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author Mei-Rong Wu
Yi Ou
Rui Han
Tian-Tian Li
Ming-Yan Wei
Hong Guo
Yao-Dong Miao
Kai Wang
Han Zhang
Lin Li
author_facet Mei-Rong Wu
Yi Ou
Rui Han
Tian-Tian Li
Ming-Yan Wei
Hong Guo
Yao-Dong Miao
Kai Wang
Han Zhang
Lin Li
author_sort Mei-Rong Wu
collection DOAJ
description Migraine is a highly prevalent neurological disorder and has been the second leading cause of disability worldwide for many years. The pathophysiology of migraines is complicated, and most available medications have unpleasant side effects. Therefore, it is essential to understand the mechanism of migraine to develop potential preventive and therapeutic agents. Studies have confirmed that traditional Chinese medicine (TCM) can alleviate migraine by reducing neuroinflammation, oxidative stress, and apoptosis and regulating neurotransmitters and vascular function. Starting from the pathophysiological process of migraine, this review summarizes the mechanisms by which TCM improves neurovascular function after migraine to provide clues and a reference for the clinical application of TCM in the prevention and treatment of migraine and guide further research and development of new drugs.
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institution DOAJ
issn 2311-8571
language English
publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series World Journal of Traditional Chinese Medicine
spelling doaj-art-98d12cedbd2e49d389d906154e66c3ec2025-08-20T02:56:30ZengWolters Kluwer Medknow PublicationsWorld Journal of Traditional Chinese Medicine2311-85712025-01-0111111510.4103/wjtcm.wjtcm_90_24Traditional Chinese Medicine Use in the Pathophysiological Processes of MigraineMei-Rong WuYi OuRui HanTian-Tian LiMing-Yan WeiHong GuoYao-Dong MiaoKai WangHan ZhangLin LiMigraine is a highly prevalent neurological disorder and has been the second leading cause of disability worldwide for many years. The pathophysiology of migraines is complicated, and most available medications have unpleasant side effects. Therefore, it is essential to understand the mechanism of migraine to develop potential preventive and therapeutic agents. Studies have confirmed that traditional Chinese medicine (TCM) can alleviate migraine by reducing neuroinflammation, oxidative stress, and apoptosis and regulating neurotransmitters and vascular function. Starting from the pathophysiological process of migraine, this review summarizes the mechanisms by which TCM improves neurovascular function after migraine to provide clues and a reference for the clinical application of TCM in the prevention and treatment of migraine and guide further research and development of new drugs.https://journals.lww.com/10.4103/wjtcm.wjtcm_90_24mechanismsmigraineneurogenic inflammationpathophysiologytraditional chinese medicinetrigeminovascular system
spellingShingle Mei-Rong Wu
Yi Ou
Rui Han
Tian-Tian Li
Ming-Yan Wei
Hong Guo
Yao-Dong Miao
Kai Wang
Han Zhang
Lin Li
Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
World Journal of Traditional Chinese Medicine
mechanisms
migraine
neurogenic inflammation
pathophysiology
traditional chinese medicine
trigeminovascular system
title Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
title_full Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
title_fullStr Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
title_full_unstemmed Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
title_short Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine
title_sort traditional chinese medicine use in the pathophysiological processes of migraine
topic mechanisms
migraine
neurogenic inflammation
pathophysiology
traditional chinese medicine
trigeminovascular system
url https://journals.lww.com/10.4103/wjtcm.wjtcm_90_24
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