Generation of two Betacellulin CRISPR-Cas9 knockout hiPSC lines to study the affected EGF system paradigm in schizophrenia

Generation of two Betacellulin CRISPR-Cas9 knockout hiPSC lines to study the affected EGF system paradigm in schizophrenia

Several members of the epidermal growth factor (EGF) family have been implicated in the biology of schizophrenia (Ketharanathan et al., 2024). The EGF-related ligand, Betacellulin (BTC), plays an important role in the proliferation and differentiation of neural stem cells and our group found markedl...

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Bibliographic Details
Main Authors: Agustin Cota-Coronado, Murray Manning, Dong-Hyung Kim, Joohyung Lee, Andrew Gibbons, Joseph Rosenbluh, Rachel A. Hill, Suresh Sundram
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506125001588
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