Hepatitis B Virus X Protein Upregulates SREBP2 to Modulate Autophagy in Hepatocellular Carcinoma

Hepatitis B Virus X Protein Upregulates SREBP2 to Modulate Autophagy in Hepatocellular Carcinoma

ABSTRACT Background The interaction between Hepatitis B virus X protein (HBx) and sterol regulatory element binding protein 2 (SREBP2) in modulating autophagy to influence inflammation and tumorigenesis is not fully understood. This research seeks to clarify the regulatory role of HBx in hepatocyte...

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Bibliographic Details
Main Authors: Qiuyan Lin, Yongxu Lin, Yongzhu Huang, Mingrong Wang, Xiaoxia Xie, Weiqi Cai, Qilan Guo, Pingying Jiang, Yuanlin Qi, Dan Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Cancer Medicine
Subjects:
autophagy
cholesterol
Hepatitis B virus X protein
hepatocellular carcinoma
sterol regulatory element binding protein 2
Online Access:https://doi.org/10.1002/cam4.70916
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