Therapeutic Potential of Ellagic Acid in Liver Diseases

Therapeutic Potential of Ellagic Acid in Liver Diseases

Ellagic acid (EA) is a natural polyphenol found in various fruits, nuts, and mushrooms. It exhibits a variety of biological activities, including potent antioxidant, anti-inflammatory, anti-obesity, and neuroprotective properties. EA exerts hepatoprotective effects through multiple mechanisms, inclu...

Full description

Saved in:

Bibliographic Details
Main Authors:	Karolina Wojtunik-Kulesza, Przemysław Niziński, Anna Krajewska, Tomasz Oniszczuk, Maciej Combrzyński, Anna Oniszczuk
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Molecules
Subjects:	polyphenols antioxidants ellagic acid urolithins MASLD
Online Access:	https://www.mdpi.com/1420-3049/30/12/2596
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Hepatoprotective Effect of Kaempferol—A Review
by: Przemysław Niziński, et al.
Published: (2025-04-01)

Quercetin: A Promising Candidate for the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
by: Julia Markowska, et al.
Published: (2024-11-01)

Potential of Quercetin as a Promising Therapeutic Agent Against Type 2 Diabetes
by: Przemysław Niziński, et al.
Published: (2025-07-01)

In vitro and in vivo antioxidant activities of three major polyphenolic compounds in pomegranate peel: Ellagic acid, punicalin, and punicalagin
by: Yu-qing SUN, et al.
Published: (2017-08-01)

Metabolomic insights into the prebiotic and metabolic regulatory properties of ellagic acid and urolithins on probiotic-like bacteria in vitro
by: Yang Yang, et al.
Published: (2025-01-01)

Fruits of Polish Medicinal Plants as Potential Sources of Natural Antioxidants: Ellagic Acid and Quercetin
by: Agnieszka Szmagara, et al.
Published: (2025-05-01)

Ellagic acid could prevent experimentally induced oxidative stress in rats
by: Mehmet Ali Kisacam, et al.
Published: (2022-12-01)

In-vivo antioxidant and therapeutic effects of ellagic acid on ischemia-reperfusion injury in skeletal muscle
by: Huseyin Demirtas, et al.
Published: (2025-03-01)

Evaluation of the Effects of Topical Ellagic Acid and Graft Application on Bone Regeneration: an Experimental Study
by: Mehmet Gül, et al.
Published: (2022-06-01)

UPLC-Q-TOF-MS/MS analysis of pomegranate peel polyphenols and preliminary study on the biosynthesis of ellagic acid and flavonoids
by: Xiaoxian Lu, et al.
Published: (2024-01-01)

Ellagic acid on milk production performance, blood and milk hormones, antioxidant capacity and fecal microbial communities in lactating Yili mares
by: Xinxin Huang, et al.
Published: (2025-08-01)

The Impact of Fresh Blueberry Addition on the Extrusion-Cooking Process, Physical Properties and Antioxidant Potential of Potato-Based Snack Pellets
by: Maciej Combrzyński, et al.
Published: (2025-05-01)

Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
by: Abhishek Chauhan, et al.
Published: (2024-09-01)

Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression
by: Aslı Bedel, et al.
Published: (2025-04-01)

Oligomeric hyaluronic acid-modified liposomes effectively improved skin permeability and anti-ageing activity of ellagic acid
by: Xiaojing Yang, et al.
Published: (2025-07-01)

Attenuating Effect of a Polyphenol Ellagic Acid on Ovarian Aging by Inhibiting the Ferroptosis Pathway in Low-Yield Laying Chickens
by: Qiongyu Yuan, et al.
Published: (2025-05-01)

Demodulation and purification of ellagic acid from pomegranate fruit and study antimicrobial activity against the pathogenic bacteria
by: Hiba H. R, et al.
Published: (2019-11-01)

Ellagic acid ameliorates renal fibrogenesis by blocking epithelial-to-mesenchymal transition
by: Po-Yu Huang, et al.
Published: (2024-01-01)

Ellagic Acid Alleviates Imidacloprid-Induced Thyroid Dysfunction via <i>PI3K/Akt/mTOR</i>-Mediated Autophagy
by: Amina A. Farag, et al.
Published: (2025-04-01)

Hydrogel-Shielded Ellagic Acid Nanoparticles Prolong Colonic Retention and Mitigate DSS-Induced Colitis via Reactive Oxygen Species Scavenging
by: Ximei Ye, et al.
Published: (2025-07-01)

Effects of Ellagic Acid and Berberine on Hind Limb Ischemia Reperfusion Injury: Pathways of Apoptosis, Pyroptosis, and Oxidative Stress
by: Esra Tekin, et al.
Published: (2025-03-01)

Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury
by: Ling Hu, et al.
Published: (2025-01-01)

Construction of Polyphenol-Collagen Crystals via Biomimetic Mineralization
by: Qiuping XIE, et al.
Published: (2025-04-01)

Design and Optimization of a Second-Generation Extruded Snack Using Carrot Waste, Blue Corn Flour, and Ellagic Acid as Functional Ingredients
by: Yaír Adonaí Sánchez-Nuño, et al.
Published: (2025-05-01)

Comparative Antioxidant and Anti-Inflammatory Activity of Ellagic Acid and <i>Juglans regia</i> L. in Collagenase-Induced Osteoarthritis in Rats
by: Alina Hanga-Farcas, et al.
Published: (2025-05-01)

Intraperitoneal injection but not oral administration of ellagic acid: a novel immunomodulator via targeting casein kinase 2 signaling pathway
by: Wenhui Qi, et al.
Published: (2025-07-01)

Urolithin A Attenuates Periodontitis in Mice via Dual Anti-Inflammatory and Osteoclastogenesis Inhibition: A Natural Metabolite-Based Therapeutic Strategy
by: Yishu Xia, et al.
Published: (2025-07-01)

Association between trans-palmitoleic acid and metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma: NHANES 1999–2018
by: Qirui Li, et al.
Published: (2025-06-01)

Urolithin A in Central Nervous System Disorders: Therapeutic Applications and Challenges
by: Qiang Zhang, et al.
Published: (2025-06-01)

Evaluating the Antiparkinsonian activity of Tamarix gallica extract in a reserpine-induced rat model of Parkinsonism: behavioral and neurochemical assessments
by: Savankumar Chhatrola, et al.
Published: (2025-04-01)

Mitigation of acrylamide in cookies and crispbread using calcium salts and phenolic acids in combination with asparaginase as well as rosemary extract
by: Shpresa Musa, et al.
Published: (2025-05-01)

In Vitro Maturation of Bovine Oocytes in the Presence of Resveratrol and Ellagic Acid but Not Chlorogenic Acid Modulates Blastocyst Antioxidant Gene Expression Without Impacting Embryo Development and Oxygen Consumption
by: Katrin Giller, et al.
Published: (2025-05-01)

Synergistic Anti-Inflammatory Effects of Pomegranate Peel–Hawthorn Combinations in Ulcerative Colitis: Network Pharmacology Prediction and Experimental Validation
by: Shouqing Zhang, et al.
Published: (2025-04-01)

Efficacy of urolithin B-Loaded mesoporous silica nanoparticles modified with graphene quantum Dots against MCF-7 breast Cancer cells
by: Bahareh Nezhadhossein, et al.
Published: (2025-07-01)

Skeletal Muscle Mitochondrial and Autophagic Dysregulation Are Modifiable in Spinal Muscular Atrophy
by: Andrew I. Mikhail, et al.
Published: (2025-02-01)

Study of two important medicinal plants, common sage and five flavor berries
by: Mohamad Hesam SHAHRAJABIAN, et al.
Published: (2024-12-01)

Impeding Minocycline Induced Hyperpigmentation by Pomegranate Extracting the Epidermis of Guinea Pig
by: Sarwath Fatimee, et al.
Published: (2021-03-01)

Design, synthesis and biological evaluation of novel urolithin derivatives targeting liver cancer cells
by: Mi Tian, et al.
Published: (2025-12-01)

Antiangiogenic Potential of Pomegranate Extracts
by: Riccardo Tornese, et al.
Published: (2024-11-01)

POLYPHENOLS, ASCORBIC ACID AND CAROTENOIDS CONTENTS AND ANTIOXIDANT PROPERTIES IN FRUITS OF CAPSICUM CHINENSE JACQ.
by: M. I. Mamedov, et al.
Published: (2017-01-01)