A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan

The study was done to show the association of high bisphenol-A levels with polycystic ovarian syndrome, keeping Pakistan in focus. Google Scholar, PubMed, ScienceDirect, and DOAJ were used for the literature search. Original research articles from 2018 to 2023 were included in this review. A total o...

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Main Authors: Ghazala Shaheen Tariq, Fozan Ahmed, Shafaq Bushra, Seemin Kashif
Format: Article
Language:English
Published: Liaquat University of Medical and Health Sciences 2024-09-01
Series:JLUMHS
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author Ghazala Shaheen Tariq
Fozan Ahmed
Shafaq Bushra
Seemin Kashif
author_facet Ghazala Shaheen Tariq
Fozan Ahmed
Shafaq Bushra
Seemin Kashif
author_sort Ghazala Shaheen Tariq
collection DOAJ
description The study was done to show the association of high bisphenol-A levels with polycystic ovarian syndrome, keeping Pakistan in focus. Google Scholar, PubMed, ScienceDirect, and DOAJ were used for the literature search. Original research articles from 2018 to 2023 were included in this review. A total of 86 articles were extracted. After exclusion, fourteen (16) articles were included in the review. No human studies were found in Pakistan, the USA, Canada, Australia, or Europe. All studies included in the review were case-control studies. Most of these studies (14) showed a positive relationship between BPA levels and PCOS, but two studies could not. No animal or human studies were found in Pakistan. Only one study was found in humans in Pakistan, which showed a direct relation between BPA levels in urine and insulin resistance in diabetic patients. According to global studies, BPA was a possible etiological factor for PCOS. No such data was obtained from Pakistan, but evidence of high levels of BPA in tap water and various canned and bottled drinks in Pakistan was found. BPA should be considered an actual threat in Pakistan at the national level. So, studies must be done, and regulations must be made to control BPA use.
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institution OA Journals
issn 1729-0341
2309-8627
language English
publishDate 2024-09-01
publisher Liaquat University of Medical and Health Sciences
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series JLUMHS
spelling doaj-art-8306bc6e40bb4860b4adae2f46be8a992025-08-20T02:12:35ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272024-09-0123318419010.22442/jlumhs.2024.01100A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on PakistanGhazala Shaheen Tariq0Fozan Ahmed1Shafaq Bushra2Seemin Kashif3Dallah Namar Hospital, Riyadh, Saudi ArabiaDepartment of Biochemistry, King Saud bin Abdulaziz University for Health Sciences, Al Ahsa, Saudi ArabiaThe Diabetes Centre, Islamabad, PakistanDepartment of Environmental Design, Health & Nutritional Sciences, Allama Iqbal Open University, Islamabad, PakistanThe study was done to show the association of high bisphenol-A levels with polycystic ovarian syndrome, keeping Pakistan in focus. Google Scholar, PubMed, ScienceDirect, and DOAJ were used for the literature search. Original research articles from 2018 to 2023 were included in this review. A total of 86 articles were extracted. After exclusion, fourteen (16) articles were included in the review. No human studies were found in Pakistan, the USA, Canada, Australia, or Europe. All studies included in the review were case-control studies. Most of these studies (14) showed a positive relationship between BPA levels and PCOS, but two studies could not. No animal or human studies were found in Pakistan. Only one study was found in humans in Pakistan, which showed a direct relation between BPA levels in urine and insulin resistance in diabetic patients. According to global studies, BPA was a possible etiological factor for PCOS. No such data was obtained from Pakistan, but evidence of high levels of BPA in tap water and various canned and bottled drinks in Pakistan was found. BPA should be considered an actual threat in Pakistan at the national level. So, studies must be done, and regulations must be made to control BPA use.polycystic ovarian syndromepcosbisphenol-aedcspakistan
spellingShingle Ghazala Shaheen Tariq
Fozan Ahmed
Shafaq Bushra
Seemin Kashif
A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
JLUMHS
polycystic ovarian syndrome
pcos
bisphenol-a
edcs
pakistan
title A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
title_full A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
title_fullStr A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
title_full_unstemmed A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
title_short A Systematic Review on the Relationship of Bisphenol-A with PCOS, with a Focus on Pakistan
title_sort systematic review on the relationship of bisphenol a with pcos with a focus on pakistan
topic polycystic ovarian syndrome
pcos
bisphenol-a
edcs
pakistan
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