Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study
Objectives: To evaluate the prevalence of high risk for obstructive sleep apnea syndrome (HR-OSAS) in Brazilian children with cerebral palsy (CP) using the Pediatric Obstructive Sleep Apnea Screening Tool (PosaST) and to analyze its association with demographic, clinical and functional (Gross Motor...
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Elsevier
2025-09-01
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| Series: | Jornal de Pediatria |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0021755725001226 |
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| author | Bruno Leonardo Scofano Dias Fernanda Marinho de Lima Daniela Fava Fernanda Jordão Pinto Marques Frederico José de Carvalho Godinho Alessandra Lemos de Carvalho Sara Virgínia Paiva Santos Fernanda de Lourdes da Cunha Pinto Danielle Bruno Jardim Wilerson Marques Bessa |
| author_facet | Bruno Leonardo Scofano Dias Fernanda Marinho de Lima Daniela Fava Fernanda Jordão Pinto Marques Frederico José de Carvalho Godinho Alessandra Lemos de Carvalho Sara Virgínia Paiva Santos Fernanda de Lourdes da Cunha Pinto Danielle Bruno Jardim Wilerson Marques Bessa |
| author_sort | Bruno Leonardo Scofano Dias |
| collection | DOAJ |
| description | Objectives: To evaluate the prevalence of high risk for obstructive sleep apnea syndrome (HR-OSAS) in Brazilian children with cerebral palsy (CP) using the Pediatric Obstructive Sleep Apnea Screening Tool (PosaST) and to analyze its association with demographic, clinical and functional (Gross Motor Function Classification System [GMFCS]) variables. Methods: Multicenter, cross-sectional, exploratory study. Results: There were 312 children (median age 6.0 years, IQR 5.0–8.0) included. The prevalence of HR-OSAS in GMFCS I-V was 9.0 %. The prevalence of HR-OSAS in GMFCS V (14.7 %) was significantly higher compared to GMFCS I-IV (6.4 %) and to the frequency of OSAS in typically developing (TD) children assessed by polysomnography (5.8 %) according to literature data. Significantly higher frequencies of palatine tonsil hypertrophy, hospitalizations and outpatient antibiotic use for respiratory causes (last 12 months), gastroesophageal reflux disease, drooling and epilepsy were found in GMFCS V. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS at the expense of its significantly higher prevalence of palatine tonsil hypertrophy. Conclusions: The prevalence of HR-OSAS in Brazilian children with CP (GMFCS V) was higher than the frequency of OSAS in TD children assessed by polysomnography. HR-OSAS was significantly more prevalent in GMFCS V compared with GMFCS I-IV. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS due to its significantly higher prevalence of palatine tonsil hypertrophy. PosaST may be a reliable questionnaire for Brazilian children with CP, but studies are needed to define the HR-OSAS cutoff score in this population. |
| format | Article |
| id | doaj-art-7dcec6ec388446e4ad5d88c2faa7c6f2 |
| institution | Kabale University |
| issn | 0021-7557 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Jornal de Pediatria |
| spelling | doaj-art-7dcec6ec388446e4ad5d88c2faa7c6f22025-08-23T04:47:20ZengElsevierJornal de Pediatria0021-75572025-09-01101510143210.1016/j.jped.2025.101432Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter studyBruno Leonardo Scofano Dias0Fernanda Marinho de Lima1Daniela Fava2Fernanda Jordão Pinto Marques3Frederico José de Carvalho Godinho4Alessandra Lemos de Carvalho5Sara Virgínia Paiva Santos6Fernanda de Lourdes da Cunha Pinto7Danielle Bruno Jardim8Wilerson Marques Bessa9Corresponding author.; Rede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilRede SARAH de Hospitais de Reabilitação, BrazilObjectives: To evaluate the prevalence of high risk for obstructive sleep apnea syndrome (HR-OSAS) in Brazilian children with cerebral palsy (CP) using the Pediatric Obstructive Sleep Apnea Screening Tool (PosaST) and to analyze its association with demographic, clinical and functional (Gross Motor Function Classification System [GMFCS]) variables. Methods: Multicenter, cross-sectional, exploratory study. Results: There were 312 children (median age 6.0 years, IQR 5.0–8.0) included. The prevalence of HR-OSAS in GMFCS I-V was 9.0 %. The prevalence of HR-OSAS in GMFCS V (14.7 %) was significantly higher compared to GMFCS I-IV (6.4 %) and to the frequency of OSAS in typically developing (TD) children assessed by polysomnography (5.8 %) according to literature data. Significantly higher frequencies of palatine tonsil hypertrophy, hospitalizations and outpatient antibiotic use for respiratory causes (last 12 months), gastroesophageal reflux disease, drooling and epilepsy were found in GMFCS V. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS at the expense of its significantly higher prevalence of palatine tonsil hypertrophy. Conclusions: The prevalence of HR-OSAS in Brazilian children with CP (GMFCS V) was higher than the frequency of OSAS in TD children assessed by polysomnography. HR-OSAS was significantly more prevalent in GMFCS V compared with GMFCS I-IV. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS due to its significantly higher prevalence of palatine tonsil hypertrophy. PosaST may be a reliable questionnaire for Brazilian children with CP, but studies are needed to define the HR-OSAS cutoff score in this population.http://www.sciencedirect.com/science/article/pii/S0021755725001226Sleep apnea, ObstructiveCerebral palsyChildrenRiskQuestionnaire |
| spellingShingle | Bruno Leonardo Scofano Dias Fernanda Marinho de Lima Daniela Fava Fernanda Jordão Pinto Marques Frederico José de Carvalho Godinho Alessandra Lemos de Carvalho Sara Virgínia Paiva Santos Fernanda de Lourdes da Cunha Pinto Danielle Bruno Jardim Wilerson Marques Bessa Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study Jornal de Pediatria Sleep apnea, Obstructive Cerebral palsy Children Risk Questionnaire |
| title | Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study |
| title_full | Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study |
| title_fullStr | Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study |
| title_full_unstemmed | Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study |
| title_short | Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study |
| title_sort | obstructive sleep apnea syndrome in children with cerebral palsy in brazil a multicenter study |
| topic | Sleep apnea, Obstructive Cerebral palsy Children Risk Questionnaire |
| url | http://www.sciencedirect.com/science/article/pii/S0021755725001226 |
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